microRNA-218 expression and its association with the clinicopathological characteristics of patients with cervical cancer
| Autor: | Jin Wang, Zhong‑Xin Lu, Shui‑Yi Liu, Li‑Qing Wei, Yu Zhan, Li Li, Bei‑Bei Tang, Xiao‑Lu Mao |
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| Jazyk: | angličtina |
| Rok vydání: | 2015 |
| Předmět: |
Oncology
Cervical cancer Cancer Research medicine.medical_specialty Pathology Oncogene business.industry Cancer General Medicine Articles medicine.disease Molecular medicine Lymphatic system Immunology and Microbiology (miscellaneous) Internal medicine medicine Stage (cooking) Family history business Pathological |
| Popis: | The aim of the present study was to investigate the expression of microRNA-218 (miRNA-218) in the serum and cervical tissue and its association with the clinicopathological features of cervical cancer (CC). The expression of miRNA-218 was detected in the serum and cervical tissue of 112 patients with CC and 50 age-matched hysteromyoma patients via the reverse transcription-quantitative polymerase chain reaction. The clinical data were collected and the association between the expression of miRNA-218 and the clinicopathological characteristics of the patients was analyzed. The expression of miRNA-218 in the cancer group was significantly decreased in the cervical tissue and serum compared with that in the control group (P |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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