Selective combination of modalities in soft tissue sarcomas: Limb salvage and survival
| Autor: | U. Rao, L. J. Emrich, Constantine P. Karakousis, M. Khalil |
|---|---|
| Rok vydání: | 1988 |
| Předmět: |
Male
medicine.medical_specialty Adjuvant chemotherapy medicine.medical_treatment Limb salvage Soft Tissue Neoplasms Methods medicine Humans Survival rate Modalities business.industry Postoperative radiation Soft tissue Extremities Sarcoma Middle Aged Combined Modality Therapy Surgery Oncology Amputation Resection margin Female Neoplasm Recurrence Local business |
| Zdroj: | Seminars in Surgical Oncology. 4:78-81 |
| ISSN: | 1098-2388 8756-0437 |
| DOI: | 10.1002/ssu.2980040115 |
| Popis: | One hundred fifty-two consecutive patients with soft tissue sarcomas were operated in the period 1977 through 1985. Eighty-seven patients with minimum resection margin of 2 cm or greater had no further local therapy, whereas 65 patients with minimum margin less than 2 cm had adjuvant postoperative radiation. Of 121 patients with extremity sarcomas, only 5 (4%) were managed with amputation. The overall 5-year survival rate is 58%, and for patients with extremity tumors, 67%. The 5-year local recurrence rate in extremity sarcomas was 10% for patients with minimum surgical margins 2 cm or greater and no further local therapy, and 6% for those with lesser surgical margins and adjuvant postoperative radiation. With selective combination of modalities limb salvage can now be practiced in 96% of the patients with acceptable local control and survival rates. |
| Databáze: | OpenAIRE |
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