Acute treatment patterns in patients with migraine newly initiating a triptan
Autor: | Hema N. Viswanathan, David W. Dodick, Jalpa A. Doshi, Richard B. Lipton, Steven C. Marcus, Anand R. Shewale |
---|---|
Jazyk: | angličtina |
Rok vydání: | 2020 |
Předmět: |
Adult
Male medicine.medical_specialty Adolescent Migraine Disorders Cohort Studies Young Adult Internal medicine Claims data medicine Humans In patient Medical prescription Aged Retrospective Studies Analgesics business.industry refill patterns migraine medication claims data General Medicine Original Articles Middle Aged medicine.disease Tryptamines Migraine Female Neurology (clinical) business Triptan persistency |
Zdroj: | Cephalalgia |
ISSN: | 1468-2982 0333-1024 |
Popis: | BackgroundTriptans are the most commonly used acute treatment for migraine. This study evaluated real-world treatment patterns following an initial triptan prescription to understand refill rates and use of non-triptan medications for the acute treatment of migraine.MethodsCommercially-insured adult patients over 18 years of age with a triptan prescription between 1/1/2013 to 31/12/2013 were identified from the Optum Clinformatics™ Data Mart database, with date of the first triptan fill designated as index date. Inclusion was limited to those with no fills for a triptan in the 12 months prior to index date (i.e. new users or initiators of triptans) and continuous enrollment in the 12 months pre- and 24 months post-index date. Fills for index triptan, non-index triptan, and other acute treatments for migraine were assessed for up to 24 months post-index.ResultsAmong 10,509 patients, 50.8% did not refill the initial triptan within 12 months and 43.6% did not refill within 24 months. In the 12 months post-index, 90.5% of patients used only one type of triptan, 8.4% used two different triptans, and 1.0% used three or more triptans. Among patients with and without a triptan refill, use of opioids (39% vs. 42%), non-steroidal anti-inflammatory drugs (22% vs. 22%), and butalbital-containing products (9% vs. 10%) were similar.ConclusionMore than half of those who newly initiated a triptan did not refill their initial prescription, and less than 1 in 10 used two or more triptans within 12 months. High rates of non-triptan acute medication use were found over 12 and 24 months of follow-up, most commonly opioids. |
Databáze: | OpenAIRE |
Externí odkaz: | |
Nepřihlášeným uživatelům se plný text nezobrazuje | K zobrazení výsledku je třeba se přihlásit. |