Prevalence and factors associated with lipodystrophy in AIDS patients

Autor: Fabiana Schuelter-Trevisol, Lunara Basqueroto Della Justina, Magali Chaves Luiz, Rosemeri Maurici
Jazyk: angličtina
Rok vydání: 2014
Předmět:
Zdroj: Revista da Sociedade Brasileira de Medicina Tropical, Vol 47, Iss 1, Pp 30-37 (2014)
Revista da Sociedade Brasileira de Medicina Tropical v.47 n.1 2014
Revista da Sociedade Brasileira de Medicina Tropical
Sociedade Brasileira de Medicina Tropical (SBMT)
instacron:SBMT
Revista da Sociedade Brasileira de Medicina Tropical, Volume: 47, Issue: 1, Pages: 30-37, Published: JAN 2014
ISSN: 1678-9849
Popis: Introduction: The published literature shows an increased occurrence of adverse events, such as human immunodeficiency virus (HIV)-associated lipodystrophy syndrome, that are associated with the continuous use of antiretroviral therapy. This study was performed to estimate the prevalence and factors associated with lipodystrophy in acquired immune deficiency syndrome (AIDS) patients. Methods: We conducted a cross-sectional study between October 2012 and February 2013. The sample consisted of patients with AIDS who attended the Outpatient Treatment Center for Infectious Diseases at Nereu Ramos Hospital, Florianópolis, State of Santa Catarina, Brazil. We collected information on demographics, lifestyle, HIV infection, and clinical aspects of the disease. Self-reported signs of lipodystrophy and body measurements were used for lipodystrophy diagnosis. Results: We studied 74 patients (mean age 44.3±9.2 years; 60.8% men). Among the patients, 45.9% were smokers, 31.1% consumed alcoholic beverages, and 55.4% were sedentary. The prevalence of lipodystrophy was 32.4%, and sedentary subjects had a higher prevalence of lipodystrophy compared with physically active individuals. Conclusions: The prevalence of lipodystrophy was 32.4%. Physical activity was considered an independent protective factor against the onset of HIV-associated lipodystrophy.
Databáze: OpenAIRE