Vulvar epithelioid leiomyoma with myxoid change: A case report and literature review
| Autor: | Si-Hyong Jang, Mee-Hye Oh, Ji-Hye Lee, Hyun Deuk Cho, Hyein Ahn, Hyun Ju Lee, Soon Auck Hong, Seong Taek Mun |
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| Rok vydání: | 2019 |
| Předmět: |
Pathology
medicine.medical_specialty Epithelioid leiomyoma Vulva 03 medical and health sciences 0302 clinical medicine Rare case Medicine Humans 030212 general & internal medicine Clinical Case Report epithelioid leiomyoma integumentary system Vulvar Neoplasms business.industry urogenital system General Medicine Leiomyoma Epithelioid Middle Aged medicine.disease female genital diseases and pregnancy complications Leiomyoma medicine.anatomical_structure smooth muscle tumor 030220 oncology & carcinogenesis Smooth Muscle Tumor Female business Myxoma Research Article |
| Zdroj: | Medicine |
| ISSN: | 1536-5964 |
| Popis: | Rationale: Smooth muscle tumors of the vulva are infrequent neoplasms with diverse histologic features and unclear biologic behavior. Herein, we report a very rare case of vulvar epithelioid leiomyoma and review of previous reported cases of these tumors. In addition, we have discussed the representative diagnostic criteria of vulvar smooth muscle tumors and prognostic significance of epithelioid morphology. Patient concerns: We recently met a 45-year-old woman with complaint of painful vulvar mass. Interventions: Excisional biopsy was performed. Diagnoses: Pathologic examination revealed a vulvar epithelioid leiomyoma with multinodular growth pattern. Mitotic activity was rare and cellular atypia was not identified. Based on histology and immunohistochemical staining results, the case was diagnosed as vulvar epithelioid leiomyoma. Outcomes: After mass excision, the patient was discharged with no complication and there was no evidence recurrence for 6 months. Lessons: After reviewing previous papers and diagnostic criterion, we thought that vulvar smooth muscle tumors with predominant epithelioid morphology may be associated with unfavorable prognosis, Therefore, pathologists should examine the epithelioid component in vulvar smooth muscle tumors carefully. |
| Databáze: | OpenAIRE |
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