Assessment of the permeability properties of cryopreservation outer bags used in NHSBT
| Autor: | P. Hogg, Paul Rooney, John N. Kearney, Richard Lomas |
|---|---|
| Rok vydání: | 2018 |
| Předmět: |
Materials science
Trace Amounts Hydrogen 040301 veterinary sciences Biomedical Engineering chemistry.chemical_element Permeability Cryopreservation 0403 veterinary science Biomaterials 03 medical and health sciences 0302 clinical medicine TRACER Product Packaging Humans Coloring Agents Drug Packaging Transplantation 030219 obstetrics & reproductive medicine Chromatography Temperature Equipment Design 04 agricultural and veterinary sciences Cell Biology Permeation Contamination Liquid nitrogen Permeability (earth sciences) chemistry Blood Preservation Blood Banks |
| Zdroj: | Cell and Tissue Banking. 19:383-389 |
| ISSN: | 1573-6814 1389-9333 |
| Popis: | This study was carried out to investigate leakage/transport across the bag material of six outer cryopreservation bags in common use within NHS Blood and Transplant. In order to do this two different leak testing procedures; coloured dye and hydrogen tracer gas, were used. The data obtained show that a coloured dye cannot permeate through the materials both at room temperature and following storage at liquid nitrogen temperature (- 196 °C). In addition, when filled with the smallest elemental molecule, hydrogen, in the form of a tracer gas, all of the bags only allowed trace amounts of hydrogen to escape, either through the seal or the bag material. The data indicated that each of the bag materials tested would be capable of preventing bacterial or viral cross-contamination as long as the material remained intact. |
| Databáze: | OpenAIRE |
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