The chameleon rash: a review of the polyphenotypic dermatoses of dermatomyositis
Autor: | A. Connolly, Patrick Gordon, Jennifer R Hannah, Daniel Creamer |
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Rok vydání: | 2021 |
Předmět: |
medicine.medical_specialty
Panniculitis Dermatology Hand Dermatoses Leg Dermatoses Dermatomyositis 030207 dermatology & venereal diseases 03 medical and health sciences 0302 clinical medicine Medicine Humans business.industry Calcinosis Torso Exanthema medicine.disease Connective tissue disease Rash Review article Idiopathic inflammatory myopathies Scalp Dermatoses 030220 oncology & carcinogenesis medicine.symptom business Facial Dermatoses |
Zdroj: | Clinical and experimental dermatologyReferences. 46(6) |
ISSN: | 1365-2230 |
Popis: | Dermatomyositis (DM) is an autoimmune connective tissue disease that is included in the idiopathic inflammatory myopathies. Cutaneous manifestations are a prominent part of the condition: some skin signs in DM are common to most patients, while other signs are encountered infrequently. A number of features are pathognomic for DM. The demonstration of myositis-specific antibodies (MSAs) in DM has extended the ability to define phenotypic subgroups. It appears that the presence of certain MSAs confers susceptibility to specific clinical features, an association which reveals a serotype-phenotype relationship. In this review article we have provided a detailed summary of common and under-recognized cutaneous manifestations of DM. |
Databáze: | OpenAIRE |
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