Interocular suppression in children with deprivation amblyopia
| Autor: | Joanna Black, Jinrong Li, Benjamin Thompson, Junpeng Yuan, Minbin Yu, Shuan Dai, Zidong Chen, Lisa M Hamm |
|---|---|
| Rok vydání: | 2017 |
| Předmět: |
Male
medicine.medical_specialty Adolescent genetic structures Visual Acuity Stimulus (physiology) Amblyopia Contrast Sensitivity Deprivation amblyopia 03 medical and health sciences 0302 clinical medicine Optics Cataracts Ophthalmology Humans Medicine In patient Child Dichoptic presentation Vision Binocular High contrast Adaptation Ocular business.industry Treatment options medicine.disease eye diseases Sensory Systems Bilateral Cataracts Child Preschool Sensory Thresholds 030221 ophthalmology & optometry Female business Photic Stimulation 030217 neurology & neurosurgery |
| Zdroj: | Vision Research. 133:112-120 |
| ISSN: | 0042-6989 |
| DOI: | 10.1016/j.visres.2017.01.004 |
| Popis: | In patients with anisometropic or strabismic amblyopia, interocular suppression can be minimized by presenting high contrast stimulus elements to the amblyopic eye and lower contrast elements to the fellow eye. This suggests a structurally intact binocular visual system that is functionally suppressed. We investigated whether suppression can also be overcome by contrast balancing in children with deprivation amblyopia due to childhood cataracts. To quantify interocular contrast balance, contrast interference thresholds were measured using an established dichoptic global motion technique for 21 children with deprivation amblyopia, 14 with anisometropic or mixed strabismic/anisometropic amblyopia and 10 visually normal children (mean age mean=9.9years, range 5-16years). We found that interocular suppression could be overcome by contrast balancing in most children with deprivation amblyopia, at least intermittently, and all children with anisometropic or mixed anisometropic/strabismic amblyopia. However, children with deprivation amblyopia due to early unilateral or bilateral cataracts could tolerate only very low contrast levels to the stronger eye indicating strong suppression. Our results suggest that treatment options reliant on contrast balanced dichoptic presentation could be attempted in a subset of children with deprivation amblyopia. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Full Text from ScienceDirect