Translational Control of Protein Synthesis in Staphylococcus aureus
| Autor: | S E Martin, J J Iandolo |
|---|---|
| Rok vydání: | 1975 |
| Předmět: |
Peptide Biosynthesis
Poly U Phenylalanine Staphylococcus Protein subunit Biology Cell Fractionation Microbiology Ribosome Cell-free system Bacterial Proteins Protein biosynthesis Carbon Radioisotopes Molecular Biology 50S chemistry.chemical_classification Cell-Free System Molecular biology Culture Media Amino acid Biochemistry chemistry Protein Biosynthesis Cell fractionation Ribosomes Research Article |
| Zdroj: | Journal of Bacteriology. 122:1136-1143 |
| ISSN: | 1098-5530 0021-9193 |
| DOI: | 10.1128/jb.122.3.1136-1143.1975 |
| Popis: | The calculated in vivo polypeptide chain growth rate for Staphylococcus auteus MF-31 grown in nutritionally rich medium assuming all the ribosomes were functional was found to be approximately 16 amino acids/s/ribosome, but decreased to 10.2 amino acids/s/ribosome for cells grown in poor medium. An in vitro analysis revealed that 70S ribosomes isolated from rich medium cells were more active than similar 70S ribosomes derived from cells grown in poor medium. The 30S subunit was found responsible for the increased activity of the rich monosomes, whereas the 50S subunit appeared to be capable of either high or low activity. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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