Early cognitive processes in OCD: An ERP study
| Autor: | Gideon E. Anholt, Andrea Berger, Adi Dayan-Riva |
|---|---|
| Rok vydání: | 2019 |
| Předmět: |
Male
Obsessive-Compulsive Disorder medicine.medical_specialty media_common.quotation_subject Stimulus (physiology) Audiology behavioral disciplines and activities Young Adult 03 medical and health sciences 0302 clinical medicine Surveys and Questionnaires Perception mental disorders medicine Humans Generalizability theory Valence (psychology) Oddball paradigm media_common Information processing Electroencephalography Cognition Event-Related Potentials P300 humanities 030227 psychiatry Psychiatry and Mental health Clinical Psychology Compulsive Behavior Quality of Life Anxiety Female medicine.symptom Cognition Disorders Psychology Psychomotor Performance 030217 neurology & neurosurgery |
| Zdroj: | Journal of Affective Disorders. 246:429-436 |
| ISSN: | 0165-0327 |
| Popis: | Background Obsessive-compulsive disorder (OCD) is characterized by persistent, intrusive, and distressing obsessions and/or compulsions and is associated with marked impairments in quality of life. The goal of the present study was to examine initial stages of information processing, specifically, perceptual and attention orientation phases that precede response preparation in OCD. Methods The P3 event-related potential (ERP) component was used as a measure of early cognitive processes of visual stimulus perception. ERPs were recorded while 38 participants diagnosed with OCD and 38 healthy controls performed a passive visual oddball task with neutral and angry schematic faces. Results OCD participants demonstrated significantly enhanced P3 amplitude over bilateral parietal areas in response to neutral stimuli that activate basic primary perceptual processes. Emotional valence reduced this effect such that OCD patients did not differ from healthy controls in P3 amplitude under the angry stimuli condition. Limitations Patients in this study were noncomorbid and unmedicated partially limiting the generalizability of the results. Conclusions Our hypothesis of altered early perceptual processes in OCD was supported. These alterations, specific to OCD and not anxiety and depression symptoms, may represent distracted primary cognitive processes in OCD, possibly serving as a basic source for compulsion initiation. |
| Databáze: | OpenAIRE |
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