Early detection of cell damage by supravital acridine orange staining
| Autor: | K. O. Söderström, Leena-Maija Parvinen, Martti Parvinen |
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| Rok vydání: | 1977 |
| Předmět: |
Male
Programmed cell death Cell Survival Phase contrast microscopy Early detection law.invention Cellular and Molecular Neuroscience chemistry.chemical_compound law Testis medicine Animals Microscopy Phase-Contrast Coloring Agents Spermatogenesis Molecular Biology Cell damage Pharmacology Staining and Labeling Chemistry Acridine orange DNA Cell Biology medicine.disease Fluorescence Molecular biology Rats Staining Microscopy Fluorescence Biochemistry Acridines Molecular Medicine |
| Zdroj: | Experientia. 33:265-266 |
| ISSN: | 1420-9071 0014-4754 |
| DOI: | 10.1007/bf02124103 |
| Popis: | Cell damage can be detected in living cells by acridine orange fluorescence earlier than with phase contrast microscopy or with conventional histological methods. The change in the acridine orange fluorescence from green to red indicates that the secondary structure of the DNA is altered very early during the cell death. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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