Are centrilobular emphysema and panlobular emphysema two different diseases?
| Autor: | Gladys A. Dart, Roger S. Mitchell, Neal Goodman, John C. Maisel, G. Wayne Silvers |
|---|---|
| Rok vydání: | 1970 |
| Předmět: |
Male
Pathology medicine.medical_specialty Lung business.industry Pulmonary emphysema Autopsy Relative weight Middle Aged respiratory system respiratory tract diseases Pathology and Forensic Medicine Diagnosis Differential medicine.anatomical_structure Pulmonary Emphysema Centrilobular emphysema Humans Medicine Female Differential diagnosis business Aged |
| Zdroj: | Human Pathology. 1:433-441 |
| ISSN: | 0046-8177 |
| DOI: | 10.1016/s0046-8177(70)80076-4 |
| Popis: | The study of the pathogenesis of emphysema would be substantially aided if two types of emphysema, centrilobular and panlobular, could be clearly identified as separate diseases with separate pathogeneses. A study was therefore undertaken to test observer agreement on emphysema typing and to determine whether clinical or radiologic differences between these two types could be identified. Emphysema typing was found to be more difficult than the published literature indicates. This experience re-emphasizes previous findings that emphysema is often mixed in type, and that a common source of disagreement in typing is the relative weight given to each type. Only one previously published difference between centrilobular and panlobular emphysema is confirmed: the former tends to be located predominantly in the upper lung whereas the latter does not. It cannot be concluded from our data that the two types either do or do not constitute separate diseases. The difference in predominant location is in favor of such a distinction but all other findings suggest no distinction. |
| Databáze: | OpenAIRE |
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