Conferring Resistance to Plant RNA Viruses with the CRISPR/CasRx System

Autor:	Fangfang Li, Huanbin Zhou, Xueping Zhou, Yongsen Cao
Rok vydání:	2021
Předmět:	Letter biology Immunology RNA RNA virus Computational biology biology.organism_classification Plant Viruses RNA Plant RNA interference Virology RNA Viruses Molecular Medicine CRISPR Clustered Regularly Interspaced Short Palindromic Repeats Functional studies CRISPR-Cas Systems Plant Diseases
Zdroj:	Virol Sin
ISSN:	1995-820X 1674-0769
DOI:	10.1007/s12250-020-00338-8
Popis:	In summary, we have established a CasRx-mediated RNA interference system which is capable of attenuating plant RNA virus infection and suppressing the expression of the target RNA. Our results greatly expand the applicability of CasRx and provide a new tool for the design of anti-viral strategies as well as for RNA functional studies in plants (Fig. 1M).
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7067902b4037b47b1cc0fd1b62b7710c https://doi.org/10.1007/s12250-020-00338-8 Zobrazit plný text záznamu Full text from SpringerLink