Impact of donor coronary angiography on kidney transplantation outcomes
| Autor: | Emilie Savoye, Cécile Vigneau, Richard Dorent, Mathieu Lesouhaitier, Camille Legeai, Marie-Alice Macher, Isabelle Pipien, Christelle Cantrelle |
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| Přispěvatelé: | CHU Pontchaillou [Rennes], Hôpital Ambroise Paré [AP-HP], Service d'urologie, andrologie et transplantation rénale, Centre Hospitalier Régional Universitaire de Besançon (CHRU Besançon)-Hôpital Saint-Jacques, Agence de la biomédecine [Saint-Denis la Plaine], AP-HP, Service de Néphrologie Pédiatrique, Hôpital Robert Debré, Paris, Institut de recherche en santé, environnement et travail (Irset), Université d'Angers (UA)-Université de Rennes 1 (UR1), Université de Rennes (UNIV-RENNES)-Université de Rennes (UNIV-RENNES)-École des Hautes Études en Santé Publique [EHESP] (EHESP)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Structure Fédérative de Recherche en Biologie et Santé de Rennes ( Biosit : Biologie - Santé - Innovation Technologique ), AP-HP - Hôpital Bichat - Claude Bernard [Paris], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP), Université d'Angers (UA)-Université de Rennes (UR)-École des Hautes Études en Santé Publique [EHESP] (EHESP)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Structure Fédérative de Recherche en Biologie et Santé de Rennes ( Biosit : Biologie - Santé - Innovation Technologique ) |
| Rok vydání: | 2018 |
| Předmět: |
Adult
Male Coronary angiography medicine.medical_specialty Tissue and Organ Procurement Adolescent Urology Contrast Media Delayed Graft Function Coronary Artery Disease 030204 cardiovascular system & hematology 030230 surgery Coronary Angiography Coronary artery disease Young Adult 03 medical and health sciences 0302 clinical medicine medicine Humans Risk factor Contraindication Kidney transplantation Aged Transplantation Kidney business.industry Incidence Gold standard Acute kidney injury Middle Aged Prognosis medicine.disease Kidney Transplantation Tissue Donors 3. Good health medicine.anatomical_structure Female France business [SDV.MHEP]Life Sciences [q-bio]/Human health and pathology Follow-Up Studies |
| Zdroj: | Clinical Transplantation Clinical Transplantation, Wiley, 2018, 32 (9), pp.e13355. ⟨10.1111/ctr.13355⟩ Clinical Transplantation, 2018, 32 (9), pp.e13355. ⟨10.1111/ctr.13355⟩ |
| ISSN: | 0902-0063 1399-0012 |
| Popis: | International audience; Coronary angiography (CA) is the gold standard evaluation of coronary artery disease in potential multi-organ donors. This use of iodinated contrast media could lead to contrast-induced acute kidney injury and consequently to delayed graft function (DGF). All patients in France who received a kidney from a 45-70-year-old donor without medical contraindication for cardiac donation and with at least one cardiovascular risk factor were included. Recipients of preemptive kidney transplant or multi-organ transplant, or who died within the first 8 days post-transplantation were excluded. Data were obtained from CRISTAL database. From March 2012 to June 2014, 892 kidneys from 483 donors were transplanted. DGF was reported in 38.9% of the 375 kidney recipients grafted with a kidney from the 217 donors who had CA and in 45.5% of the 440 kidney recipients who received a kidney from the 257 donors without CA. Multivariate analysis showed that CA or repeated injection of iodinated contrast media did not influence the risk of DGF. CA did not increase the risk of primary non-function, the duration of DGF or post-transplantation hospital stay and did not affect the graft function at 1 year. Evaluation of potential multi-organ donors with CA does not affect kidney graft outcomes. |
| Databáze: | OpenAIRE |
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