Intraoperative injection of technetium-99m sulfur colloid is effective in the detection of sentinel lymph nodes in breast cancer
| Autor: | Hernan I. Vargas, Christine Dauphine, M. Perla Vargas, Iraj Khalkhali, Jason S. Haukoos, Nova M. Isaac |
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| Rok vydání: | 2006 |
| Předmět: |
Mammary gland
Sentinel lymph node chemistry.chemical_element Breast Neoplasms Technetium Drug Administration Schedule Cohort Studies Breast cancer Biopsy medicine Humans Radionuclide Imaging Neoplasm Staging Retrospective Studies Intraoperative Care medicine.diagnostic_test Sentinel Lymph Node Biopsy business.industry Technetium 99m sulfur colloid General Medicine Middle Aged Sentinel node medicine.disease body regions medicine.anatomical_structure chemistry Technetium Tc 99m Sulfur Colloid Female Surgery Lymph Nodes Lymph Radiopharmaceuticals business Nuclear medicine |
| Zdroj: | The American Journal of Surgery. 192:423-426 |
| ISSN: | 0002-9610 |
| Popis: | Background Our objective was to determine if intraoperative injection of technetium-99m–labeled sulfur colloid is as effective as preoperative injection in the detection of sentinel lymph nodes (SLNs). Methods Two hundred consecutive patients with breast cancer underwent SLN biopsy examination. Radiocolloid was injected in the preoperative area (group A) or immediately after induction of anesthesia in the operating room (group B). Results The SLN detection rate was similar for groups A (96%) and B (100%; P = .2). Radioactive SLNs were detected in 95% of patients in group A and in 97% of patients in group B (P = .1). The mean number of SLNs harvested was 1.6 and 2.1 for groups A and B, respectively. There was no significant difference in positive SLNs between groups (P = .11). Conclusions Intraoperative injection of sulfur colloid is highly effective in the detection of SLNs, avoiding patient discomfort and surgical schedule delays. |
| Databáze: | OpenAIRE |
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