Real-Time Impedance Detection of Intra-Articular Space in a Porcine Model Using a Monopolar Injection Needle
| Autor: | Ki Deok Park, Somasekhar R. Chinnadayyala, Sungbo Cho, Hwijung Kim, Muhammad Aitzaz Abbasi |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2020 |
| Předmět: |
musculoskeletal diseases
Materials science monopolar injection needle Knee Joint Swine 0206 medical engineering 02 engineering and technology lcsh:Chemical technology Biochemistry Article Analytical Chemistry Injections Intra-Articular Intra articular medicine Electric Impedance Fluoroscopy Animals lcsh:TP1-1185 Electrical and Electronic Engineering Instrumentation Electrical impedance porcine model intra-articular injection medicine.diagnostic_test business.industry Focused Impedance Measurement Biological tissue ultrasonography 021001 nanoscience & nanotechnology musculoskeletal system 020601 biomedical engineering Atomic and Molecular Physics and Optics fluoroscopy Needles electrical impedance monitoring Models Animal Ultrasonography 0210 nano-technology business Biomedical engineering |
| Zdroj: | Sensors, Vol 20, Iss 4625, p 4625 (2020) Sensors Volume 20 Issue 16 Sensors (Basel, Switzerland) |
| ISSN: | 1424-8220 |
| Popis: | Rheumatoid arthritis and osteoarthritis can be treated through specific drug injection into the intra-articular space. Several failures during drug injection attempts with conventional fluoroscopy and ultrasonography in a small area of the intra-articular space have been reported. In this work we present an innovative impedance measurement-based method/algorithm for needle tip positioning to enhance image-guided intra-articular vaccination treatment. A novel algorithm for detecting the intra-articular space in the elbow and knee joints of a live porcine model is reported. An impedance measurement system was developed for biological tissue measurement. The electrical impedance in the intra-articular space was monitored and the needle tip was examined by ultrasonography. The contrast dye was vaccinated and checked using fluoroscopy to confirm that the dye was properly inoculated in the cavity. The electrical impedance was estimated for various needle inclusion profundity levels in saline solution, which were broadly used to evaluate the proposed device for in vivo examinations. Good efficiency was observed in the impedance-based measurements using a monopolar injection needle for intra-articular therapy. To enhance the needle tip positioning for intra-articular therapy, the intended impedance measurement device with a monopolar injection needle can be used as a complement to existing modalities. |
| Databáze: | OpenAIRE |
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