Stereochemical aspects and the synthetic scope of the SHi at the sulfur atom. Preparation of enantiopure 3-substituted 2,3-dihydro-1,2- benzoisothiazole 1-oxides and 1,1-dioxides
| Autor: | M. Mercedes Rodriguez‐Fernandez, José L. García-Ruano, José A. Fernández-Salas, M. Carmen Maestro |
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| Přispěvatelé: | UAM. Departamento de Química Orgánica |
| Jazyk: | angličtina |
| Rok vydání: | 2014 |
| Předmět: |
Scope (project management)
Complete inversion Chemistry Sulfinamide Substitution (logic) Metals and Alloys chemistry.chemical_element General Chemistry Química Sulfonamide Sulfoxide Sulfur Catalysis Surfaces Coatings and Films Electronic Optical and Magnetic Materials Homolysis Enantiopure drug Computational chemistry Intramolecular force Materials Chemistry Ceramics and Composites Organic chemistry |
| Zdroj: | Biblos-e Archivo. Repositorio Institucional de la UAM instname |
| DOI: | 10.1039/c4cc01831a |
| Popis: | Intramolecular homolytic substitution (SHi) on the sulfur atom at acyclic N-(o-bromobenzyl)sulfinamides takes place with a complete inversion of the configuration and provides an excellent tool to connect N-tert-butanesulfinylimines with enantiopure 3-substituted benzo-fused sulfinamides (1,2-benzoisothiazoline 1-oxides) and the related pharmacologically relevant sulfonamides The Spanish Government (grant CTQ2012-35957) and Comunidad de Madrid (CCG08-UAM/PPQ-4151; S2009/PPQ1634) |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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