Hepato nephropathology associated with inclusion body hepatitis complicated with citrinin mycotoxicosis in a broiler farm
Autor: | Shambu Dayal Singh, Palanivelu Munusamy, Asok Kumar Mariappan, Kuldeep Dhama, Shyma K. Latheef |
---|---|
Jazyk: | angličtina |
Rok vydání: | 2018 |
Předmět: |
Pathology
medicine.medical_specialty Myocarditis animal structures inclusion body hepatitis 040301 veterinary sciences Veterinary medicine Population SF1-1100 0403 veterinary science chemistry.chemical_compound SF600-1100 medicine Mycotoxicosis education Hepatitis education.field_of_study General Veterinary business.industry thin-layer chromatography 0402 animal and dairy science 04 agricultural and veterinary sciences citrinin medicine.disease 040201 dairy & animal science Animal culture Citrinin Renal pathology chemistry fowl adenovirus Flock business Nephritis glomerulonephritis Research Article |
Zdroj: | Veterinary World Veterinary World, Vol 11, Iss 2, Pp 112-117 (2018) |
ISSN: | 2231-0916 0972-8988 |
Popis: | Aim: Mortality in a broiler chicken farm was investigated for identifying the cause of mortality. Materials and Methods: A broiler farm with a population of 16000 succumbed to a disease outbreak. Clinical signs, vaccination history and mortality, were recorded. Necropsy examination and microscopic examination were carried out along with toxicological and molecular studies. Results: The clinical signs in the affected broiler birds were of non-specific nature with a total mortality of 26.39%. Postmortem examination and microscopical findings revealed hepatitis with basophilic intranuclear inclusion, splenitis, myocarditis, and nephritis. Glomerulonephritis was the prominent renal pathology recorded in this study. Polymerase chain reaction test confirmed the presence of fowl adenovirus (FAdV) genome in the target organs, and toxicological examination by thin-layer chromatography revealed the presence of a toxic level of citrinin in the feed samples. Conclusion: Based on various diagnostic investigations, the mortality in the flock was attributed to inclusion body hepatitis (IBH) complicated with citrinin mycotoxicosis. Thus, apart from liver pathology which occurs in a classical IBH cases, glomerulonephritis too occurs which are also a prominent finding which pathologists often miss. Thus, kidneys should also be examined histologically to assess the microscopic tissue alterations in poultry suspected for IBH along with a mycotoxicological analysis of feed. This will definitely throw light on the synergistic pathology elicited and exhibited by FAdV and mycotoxins in the poultry. |
Databáze: | OpenAIRE |
Externí odkaz: |