The homeodomain transcription factor Ste12

Autor:	Antonio Di Pietro, Nicolas Rispail
Přispěvatelé:	European Commission, Ministerio de Ciencia e Innovación (España)
Rok vydání:	2010
Předmět:	MAPK/ERK pathway Virulence MAPK cascade Reviews Ste12 Biology Bioinformatics Signaling Yeast 3. Good health Cell biology Plant pathogen Homeobox Fungal pathogenicity Signal transduction General Agricultural and Biological Sciences Protein kinase A Transcription factor
Zdroj:	Communitative and Integrative Biology 3(4): 327-332 (2010) Helvia. Repositorio Institucional de la Universidad de Córdoba instname Digital.CSIC. Repositorio Institucional del CSIC
ISSN:	1942-0889
DOI:	10.4161/cib.3.4.11908
Popis:	A conserved mitogen-activated protein kinase (MAPK) cascade orthologous to the mating/filamentation MAPK pathway in yeast is required for fungal pathogenicity on plants. One of the key targets of this signaling pathway is the homeodomain transcription factor Ste12. Mutational analysis of ste12 orthologues in a variety of plant pathogenic fungi suggests that Ste12 functions as a master regulator of invasive growth. In this mini-review we highlight recent progress in understanding the role of Ste12 in filamentous fungi and discuss future challenges of unravelling the mechanisms by which Ste12 controls fungal virulence downstream of the Pathogenicity MAPK cascade. © 2010 Landes Bioscience. Research in the group of A.D.P. is supported by projects SIGNALPATH (MRTN-CT-2005-019277) and ARIADNE (FP7-PEOPLE-ITN-2008-237936) from the European Commission and by grant BIO2007-62661 from the Spanish Ministerio de Ciencia e Innovación (MICINN).
Databáze:	OpenAIRE
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