Human Papillomavirus Vaccination and Infection in Young Sexual Minority Men: The P18 Cohort Study
| Autor: | Stephen E. Goldstone, Farzana Kapadia, Danielle C. Ompad, Maria Kanztanou, Pamela Valera, Caleb LoSchiavo, Richard E. Greene, Anthony J. Maiolatesi, Perry N. Halkitis |
|---|---|
| Rok vydání: | 2019 |
| Předmět: |
Adult
Male Human immunodeficiency virus (HIV) Anal Canal HIV Infections medicine.disease_cause Men who have sex with men Cohort Studies 03 medical and health sciences Sexual and Gender Minorities Young Adult 0302 clinical medicine Surveys and Questionnaires medicine Ethnicity Prevalence Humans 030212 general & internal medicine Papillomavirus Vaccines Prospective Studies Homosexuality Male Papillomaviridae Minority Groups 030505 public health business.industry Clinical and Epidemiologic Research Papillomavirus Infections Vaccination Public Health Environmental and Occupational Health Cancer virus diseases medicine.disease Human papillomavirus vaccination female genital diseases and pregnancy complications Sexual minority Infectious Diseases Cohort Bisexuality Female 0305 other medical science business Demography Cohort study |
| Zdroj: | AIDS patient care and STDs. 33(4) |
| ISSN: | 1557-7449 |
| Popis: | We examined the prevalence of infection with human papillomavirus (HPV) and HIV in a cohort of young gay, bisexual, and other men who have sex with men [sexual minority men (SMM)]. HPV vaccination uptake was assessed; HIV antibody testing was performed and genetic testing for oral and anal HPV infection was undertaken. We examined both HPV vaccination and infection in relation to key demographic and structural variables. Participants (n = 486) were on average 23 years old; 70% identified as a member of a racial/ethnic minority group, and 7% identified as transgender females. Only 18.1% of the participants indicated having received the full dosage of HPV vaccination and 45.1% were unvaccinated. Slightly over half the participants (58.6%) were infected with HPV, with 58.1% testing positive for anal infection and 8.8% for oral infection. HIV seropositivity was associated with infection to oral HPV [adjusted odds ratio (AOR) = 4.03] and vaccine-preventable HPV, whereas both neighborhood-level poverty (AOR = 1.68) and HIV infection (AOR = 31.13) were associated with anal infection to HPV (AOR = 1.68). Prevalence of HPV infection is high among unvaccinated young SMM, despite the availability and eligibility for vaccination. HPV infection adds further health burden to these populations and is particularly concerning for those who are HIV positive as HIV infection increases the risk of developing HPV-related cancers. These findings underscore a missed prevention opportunity for an at-risk and underserved population and suggest the need for active strategies to increase HPV vaccination uptake in young SMM before the onset of sexual behavior. |
| Databáze: | OpenAIRE |
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