Guidelines for Perioperative Care for Liver Transplantation: Enhanced Recovery After Surgery (ERAS) Recommendations

Autor: Nicolas Demartines, Olivier Scatton, Helen Usher, Stephen J. Wigmore, Damiano Patrono, Eduardo Schiffer, Raffaele Brustia, Wellington Andraus, Emily Baird, Olivier Detry, Marieke T. de Boer, Stefano Skurzak, Gonzalo Rodriguez Laiz, Antoine Monsel, François Martin Carrier, Franck Vandenbroucke-Menu, Paulo Melgar, Philippe Compagnon, Abdourahamane Kaba, Luiz Marcelo Sá Malbouisson, Miriam Zeillemaker-Hoekstra, Gianni Biancofiore, Toshimi Kaido, Shinji Uemoto, Koen Reyntjen, Susan L. Orloff, Carlijn I. Buis
Jazyk: angličtina
Rok vydání: 2022
Předmět:
Zdroj: Transplantation, 106(3), 552-561. LIPPINCOTT WILLIAMS & WILKINS
Transplantation (2021)
Transplantation
r-ISABIAL. Repositorio Institucional de Producción Científica del Instituto de Investigación Biomédica y Sanitaria de Alicante
instname
ISSN: 0041-1337
Popis: BACKGROUND: Enhanced Recovery After Surgery (ERAS) is a multimodal, evidence-based, program of care developed to minimize the response to surgical stress, associated with reduced perioperative morbidity and hospital stay. This study presents the specific ERAS Society recommendations for liver transplantation (LT) based on the best available evidence and on expert consensus. METHODS: PubMed and ClinicalTrials.gov were searched in April 2019 for published and ongoing RCTs on LT in the last 15 years. Studies were selected by 5 independent reviewers, and were eligible if focusing on each validated ERAS items in the area of adult LT. An e-Delphi method was used with an extended interdisciplinary panel of experts to validate the final recommendations. RESULTS: Forty-three articles were included in the systematic review. Consensus was reached among experts after the second round. Patients should be screened for malnutrition and treated whenever possible. Prophylactic nasogastric intubation and prophylactic abdominal drainage may be omitted, and early extubation should be considered. Early oral intake, mobilization and multimodal-balanced analgesia are recommended. CONCLUSIONS: The current ERAS recommendations were elaborated based on the best available evidence and endorsed by the e-Delphi method. Nevertheless, prospective studies need to confirm the clinical use of the suggested protocol.PROSPERO CRD4201913279.
Databáze: OpenAIRE