Long-term study of recurrent vasospastic angina using coronary angiograms during ergonovine provocation tests
| Autor: | Takafumi Anno, Munetaka Sugiishi, Yukio Ozaki, Masato Watarai, Fumimaro Takatsu, Junji Toyama, Junichi Osugi |
|---|---|
| Rok vydání: | 1992 |
| Předmět: |
Adult
Angina Pectoris Variant Male medicine.medical_specialty Time Factors Provocation test Coronary Vasospasm Coronary Angiography Angina Recurrence Internal medicine Medicine Humans Ergometrine cardiovascular diseases Angiocardiography Ergonovine Aged First episode medicine.diagnostic_test business.industry Middle Aged medicine.disease Anesthesia Angiography Cardiology Female Cardiology and Cardiovascular Medicine business Electrocardiography medicine.drug |
| Zdroj: | American heart journal. 123(5) |
| ISSN: | 0002-8703 |
| Popis: | Chronologic changes of coronary spasm were examined by repeated ergonovine provocation tests during angiography. A total of 322 patients who had variant angina without severe atherosclerosis demonstrated a positive response to the first test. Ninety of these patients had recurrent variant anginal symptoms after an angina-free period of 38 +/- 12 months (mean +/- SD). Of these 90 patients, 76 (84%) had symptoms or electrocardiographic (ECG) findings similar to those of the first test. The initial 9 of these 76 patients underwent a second provocation test and showed coronary responses analogous to those on the first test. Of the 90 patients, 14 (16%) had different symptoms or ECG findings from those elicited at the first episode. All 14 patients again had a positive response to a second ergonovine test and the following angiographic changes were observed in the three major vessels between the two tests. Of the 21 vessels that had spasm on the first test, eight vessels (19%) did not have spasm on the second test. Of the 21 vessels that did not demonstrate spasm on the first test, 10 (24%) demonstrated spasm on the second test. In the present study it is concluded that the majority of patients with recurrent angina seemed to have consistency in the location of coronary spasm, while in some patients the fluctuation of coronary spasm was confirmed by two ergonovine provocation tests. |
| Databáze: | OpenAIRE |
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