Creatinine clearance: an inadequate marker of renal filtration in patients with early posthepatitic cirrhosis (Child A) without fluid retention and muscle wasting
| Autor: | DESANTO NG, ANASTASIO, Pietro, LOGUERCIO, Carmelina, SPITALI L, DEL VECCHIO BLANCO C, CORVINELLI M, GIRILLO MRELATED ARTICLES, LINKS |
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| Přispěvatelé: | Desanto, Ng, Anastasio, P, Loguercio, C, Spitali, L, Del Vecchio Blanco, C, Corvinelli, M, Cirillo, M., Anastasio, Pietro, Loguercio, Carmelina, DEL VECCHIO BLANCO, C, GIRILLO MRELATED, Article, Links |
| Jazyk: | angličtina |
| Rok vydání: | 1995 |
| Předmět: |
Liver Cirrhosis
Male medicine.medical_specialty Cirrhosis Urology Renal function urologic and male genital diseases Hepatitis chemistry.chemical_compound Internal medicine medicine Humans Wasting Creatinine Inulin Clearance urogenital system business.industry Inulin creatinine Posthepatitic cirrhosis Middle Aged medicine.disease Endocrinology chemistry Renal physiology Female medicine.symptom Complication business Biomarkers Glomerular Filtration Rate |
| Zdroj: | Europe PubMed Central |
| Popis: | Glomerular filtration rate (GFR) was measured in 19 patients with Child A liver cirrhosis by comparing the endogenous creatinine clearance with inulin clearance. Inulin clearance averaged 90 +/- 4.4 ml/min x 1.73 m2, while creatinine clearance averaged 122 +/- 7 ml/min x 1.73 m2 (p < 0.001). The overestimation of GFR by creatinine was present in 18 of 19 patients and was inversely correlated with inulin clearance (r = -0.452, p < 0.04). The data point to the unsuitability of creatinine as a marker of filtration in early posthepatitic cirrhosis (Child A). |
| Databáze: | OpenAIRE |
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