Evaluation of procalcitonin and CRP as sepsis markers in 74 consecutive patients admitted with prolonged febrile neutropenia
| Autor: | Jérôme Cornillon, Marie Bouteloup, C. Lambert |
|---|---|
| Přispěvatelé: | Institut de Cancérologie de la Loire Lucien Neuwirth, Centre Hospitalier Universitaire de Saint-Etienne (CHU de Saint-Etienne), Laboratoire d'Immunologie, CHU Saint Etienne, Centre Ingénierie et Santé (CIS-ENSMSE), École des Mines de Saint-Étienne (Mines Saint-Étienne MSE), Institut Mines-Télécom [Paris] (IMT)-Institut Mines-Télécom [Paris] (IMT), Axe projet 'dynamique des systèmes biologiques' (DSB-ENSMSE), Institut Mines-Télécom [Paris] (IMT)-Institut Mines-Télécom [Paris] (IMT)-CIS, Laboratoire des Procédés en Milieux Granulaires (LPMG-EMSE), Institut Mines-Télécom [Paris] (IMT)-Institut Mines-Télécom [Paris] (IMT)-Centre National de la Recherche Scientifique (CNRS), Institut Fédératif de Recherche en Sciences et Ingénierie de la Santé (IFRESIS-ENSMSE), Institut Mines-Télécom [Paris] (IMT)-Institut Mines-Télécom [Paris] (IMT)-IFR143, Institut de Cancérologie de la Loire |
| Rok vydání: | 2011 |
| Předmět: |
Calcitonin
Microbiology (medical) medicine.medical_specialty medicine.drug_class Antibiotics Inflammation Infections Procalcitonin Sepsis medicine Humans Protein Precursors Stage (cooking) Intensive care medicine fever Critically ill business.industry medicine.disease Infectious Diseases bacterial infections marker of inflammation [SDV.IMM]Life Sciences [q-bio]/Immunology medicine.symptom CRP PCT business procalcitonin Febrile neutropenia |
| Zdroj: | Journal of Infection Journal of Infection, WB Saunders, 2011, 63 (1), pp.93-95. ⟨10.1016/j.jinf.2011.05.010⟩ |
| ISSN: | 0163-4453 |
| DOI: | 10.1016/j.jinf.2011.05.010 |
| Popis: | International audience; Fever is a major event in critically ill patients. Its causes are difficult to identify and among them, bacterial infections must be rapidly identified and treated before sepsis reach a life threatening stage. CRP is a very sensitive marker of inflammation of whatever causes including sepsis. This is particularly crucial in immunocompromised patients. On the other hand, PCT has been extensively shown to be strongly and rapidly produced in bacterial infections only. Furthermore, PCT decreases very soon after bacterial resolution, and is thus a very useful in monitoring adequacy and efficiency of antibiotics. The utility of this marker in sever sepsis is now widely admitted. |
| Databáze: | OpenAIRE |
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