In Vitro Phytotherapeutic Properties of Aqueous Extracted Adenia viridiflora Craib. towards Civilization Diseases
Autor: | Piya Temviriyanukul, Chaowanee Chupeerach, Somsri Charoenkiatkul, Werawat Wannasaksri, Uthaiwan Suttisansanee, Nattira On-Nom |
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Rok vydání: | 2021 |
Předmět: |
Adenia
Naringenin Adenia viridiflora Craib Flavonoid Endangered species Pharmaceutical Science 01 natural sciences Antioxidants Analytical Chemistry chemistry.chemical_compound Drug Discovery phenolic compositions antioxidant activities Disease Enzyme Inhibitors Passifloraceae Chromatography High Pressure Liquid Candida chemistry.chemical_classification biology Traditional medicine food and beverages 04 agricultural and veterinary sciences 040401 food science young shoots Chemistry (miscellaneous) Hypertension Shoot Apigenin Molecular Medicine Rabbits Plant Shoots food.ingredient old leaves Saccharomyces cerevisiae Article lcsh:QD241-441 0404 agricultural biotechnology food lcsh:Organic chemistry Phenols medicine Animals Humans Horses Physical and Theoretical Chemistry Flavonoids Plant Extracts 010401 analytical chemistry Organic Chemistry Water medicine.disease biology.organism_classification Obesity 0104 chemical sciences Plant Leaves chemistry Herb Solvents enzyme inhibitory activities Phytotherapy |
Zdroj: | Molecules Molecules, Vol 26, Iss 1082, p 1082 (2021) Volume 26 Issue 4 |
ISSN: | 1420-3049 |
DOI: | 10.3390/molecules26041082 |
Popis: | Adenia viridiflora Craib. is an indigenous edible plant that became an endangered species due to limited consumption of the local population with unknown reproduction and growth conditions. The plant is used as a traditional herb however, its health applications lack scientific-based evidence. A. viridiflora Craib. plant parts (old leaves and young shoots) from four areas as Kamphaeng Phet (KP), Muang Nakhon Ratchasima (MN), Pakchong Nakhon Ratchasima (PN), and Uthai Thani (UT) origins were investigated for phenolic compositions and in vitro health properties through the inhibition of key enzymes relevant to obesity (lipase), diabetes (α-glucosidase and dipeptidyl peptidase-IV), Alzheimer’s disease (cholinesterases and β-secretase), and hypertension (angiotensin-converting enzyme). Phenolics including p-coumaric acid, sinapic acid, naringenin, and apigenin were detected in old leaves and young shoots in all plant origins. Old leaves exhibited higher total phenolic contents (TPCs) and total flavonoid contents (TFCs), leading to higher enzyme inhibitory activities than young shoots. Besides, PN and MN with higher TPCs and TFCs tended to exhibit greater enzyme inhibitory activities than others. These results will be useful to promote this plant as a healthy food with valuable medicinal capacities to support its consumption and agricultural stimulation, leading to sustainable conservation of this endangered species. |
Databáze: | OpenAIRE |
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