In Vitro Phytotherapeutic Properties of Aqueous Extracted Adenia viridiflora Craib. towards Civilization Diseases

Autor: Piya Temviriyanukul, Chaowanee Chupeerach, Somsri Charoenkiatkul, Werawat Wannasaksri, Uthaiwan Suttisansanee, Nattira On-Nom
Rok vydání: 2021
Předmět:
Adenia
Naringenin
Adenia viridiflora Craib
Flavonoid
Endangered species
Pharmaceutical Science
01 natural sciences
Antioxidants
Analytical Chemistry
chemistry.chemical_compound
Drug Discovery
phenolic compositions
antioxidant activities

Disease
Enzyme Inhibitors
Passifloraceae
Chromatography
High Pressure Liquid

Candida
chemistry.chemical_classification
biology
Traditional medicine
food and beverages
04 agricultural and veterinary sciences
040401 food science
young shoots
Chemistry (miscellaneous)
Hypertension
Shoot
Apigenin
Molecular Medicine
Rabbits
Plant Shoots
food.ingredient
old leaves
Saccharomyces cerevisiae
Article
lcsh:QD241-441
0404 agricultural biotechnology
food
lcsh:Organic chemistry
Phenols
medicine
Animals
Humans
Horses
Physical and Theoretical Chemistry
Flavonoids
Plant Extracts
010401 analytical chemistry
Organic Chemistry
Water
medicine.disease
biology.organism_classification
Obesity
0104 chemical sciences
Plant Leaves
chemistry
Herb
Solvents
enzyme inhibitory activities
Phytotherapy
Zdroj: Molecules
Molecules, Vol 26, Iss 1082, p 1082 (2021)
Volume 26
Issue 4
ISSN: 1420-3049
DOI: 10.3390/molecules26041082
Popis: Adenia viridiflora Craib. is an indigenous edible plant that became an endangered species due to limited consumption of the local population with unknown reproduction and growth conditions. The plant is used as a traditional herb
however, its health applications lack scientific-based evidence. A. viridiflora Craib. plant parts (old leaves and young shoots) from four areas as Kamphaeng Phet (KP), Muang Nakhon Ratchasima (MN), Pakchong Nakhon Ratchasima (PN), and Uthai Thani (UT) origins were investigated for phenolic compositions and in vitro health properties through the inhibition of key enzymes relevant to obesity (lipase), diabetes (α-glucosidase and dipeptidyl peptidase-IV), Alzheimer’s disease (cholinesterases and β-secretase), and hypertension (angiotensin-converting enzyme). Phenolics including p-coumaric acid, sinapic acid, naringenin, and apigenin were detected in old leaves and young shoots in all plant origins. Old leaves exhibited higher total phenolic contents (TPCs) and total flavonoid contents (TFCs), leading to higher enzyme inhibitory activities than young shoots. Besides, PN and MN with higher TPCs and TFCs tended to exhibit greater enzyme inhibitory activities than others. These results will be useful to promote this plant as a healthy food with valuable medicinal capacities to support its consumption and agricultural stimulation, leading to sustainable conservation of this endangered species.
Databáze: OpenAIRE
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