Perioperative nutritional aspects in total pancreatectomy: A comprehensive review of the literature

Autor: Giulio Di Candio, Niccolò Furbetta, Gregorio Di Franco, Luca Morelli, Simone Guadagni, Desirée Gianardi, Matteo Palmeri, Annalisa Comandatore, Lorenzo Maria Fatucchi, Matteo Bianchini, Martina Picchi, Luca Bastiani, Giovanni Caprili, Giandomenico Luigi Biancofiore
Jazyk: angličtina
Rok vydání: 2021
Předmět:
Male
medicine.medical_specialty
Sarcopenia
Total pancreatectomy
medicine.medical_treatment
Islets of Langerhans Transplantation
Total pancreatectomy with islet auto-transplantation
Nutritional Status
Review
Cachexia
Body Mass Index
03 medical and health sciences
0302 clinical medicine
Pancreatectomy
Postoperative Complications
Risk Factors
Pancreatitis
Chronic
medicine
Nutrition
Nutritional status
Nutritional support
Female
Humans
Nutrition Therapy
Pancreatic Neoplasms
Prognosis
Serum Albumin
TX341-641
Medical nutrition therapy
Pancreatitis
chronic
Chronic
Intensive care medicine
Glycemic
Nutrition and Dietetics
Nutrition. Foods and food supply
business.industry
Perioperative
medicine.disease
Parenteral nutrition
Pancreatitis
030220 oncology & carcinogenesis
030211 gastroenterology & hepatology
business
Food Science
Zdroj: Nutrients, Vol 13, Iss 1765, p 1765 (2021)
Nutrients
Popis: Total pancreatectomy (TP) is a highly invasive procedure often performed in patients affected by anorexia, malabsorption, cachexia, and malnutrition, which are risk factors for bad surgical outcome and even may cause enhanced toxicity to chemo-radiotherapy. The role of nutritional therapies and the association between nutritional aspects and the outcome of patients who have undergone TP is described in some studies. The aim of this comprehensive review is to summarize the available recent evidence about the influence of nutritional factors in TP. Preoperative nutritional and metabolic assessment, but also intra-operative and post-operative nutritional therapies and their consequences, are analyzed in order to identify the aspects that can influence the outcome of patients undergoing TP. The results of this review show that preoperative nutritional status, sarcopenia, BMI and serum albumin are prognostic factors both in TP for pancreatic cancer to support chemotherapy, prevent recurrence and prolong survival, and in TP with islet auto-transplantation for chronic pancreatitis to improve postoperative glycemic control and obtain better outcomes. When it is possible, enteral nutrition is always preferable to parenteral nutrition, with the aim to prevent or reduce cachexia. Nowadays, the nutritional consequences of TP, including diabetes control, are improved and become more manageable.
Databáze: OpenAIRE
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