The post-trial analysis of the Indian SMS diabetes prevention study shows persistent beneficial effects of lifestyle intervention
| Autor: | Ian F. Godsland, Priscilla Susairaj, Arun Nanditha, Ramachandran Vinitha, Chamukuttan Snehalatha, Desmond G. Johnston, Mary Simon, Jagannathan Ram, Krishnamoorthy Satheesh, Ambady Ramachandran, Addagarla P. Naveen Kumar, Nick Oliver, Arun Raghavan, Sundaram Selvam |
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| Rok vydání: | 2018 |
| Předmět: |
Adult
Male Relative risk reduction medicine.medical_specialty Endocrinology Diabetes and Metabolism Health Behavior 030209 endocrinology & metabolism Type 2 diabetes law.invention 03 medical and health sciences 0302 clinical medicine Endocrinology Asian People Randomized controlled trial law Intervention (counseling) Diabetes mellitus Lifestyle intervention Internal Medicine Humans Medicine 030212 general & internal medicine Life Style Beneficial effects Text Messaging business.industry Incidence (epidemiology) General Medicine Glucose Tolerance Test Middle Aged medicine.disease Diet Diabetes Mellitus Type 2 Physical therapy business Risk Reduction Behavior Cell Phone |
| Zdroj: | Diabetes Research and Clinical Practice. 142:213-221 |
| ISSN: | 0168-8227 |
| Popis: | Aims We had shown that mobile phone based text messaging was an effective tool to deliver lifestyle changes among Asian Indian men with a 36% relative risk reduction in incident diabetes over two years. The present analysis investigated whether beneficial effects of intervention on diabetes prevention persisted for an additional three years after withdrawal of active intervention. Methods The primary two year randomized controlled trial (2010–2012) compared lifestyle changes with use of automated text messaging reminders in the intervention (n = 271) versus standard care advice (n = 266) at baseline. At the end of the study, both groups received additional advice on lifestyle changes by a trained dietician. Participants free of diabetes (n = 394) were invited three years later to ascertain the sustained effect of intervention. The primary outcome was incidence of type 2 diabetes. This trial is registered with ClinicalTrials.gov,number NCT02848547. Results During the mean follow-up of 5 years, 346 out of 394 (87.8%) men were reviewed. Incidence of diabetes was reduced by 30% in the intervention group, with declining gap between-group differences over time (Kaplan-Meier analysis). Significant improvement in dietary adherence occurred in the intervention group at 2nd and 5th year follow up (trend χ2 = 21.35, p Conclusions Sustained reduction in incident diabetes was apparent after cessation of active lifestyle intervention. This was possibly associated with continuing practice of improved lifestyle. |
| Databáze: | OpenAIRE |
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