ZnO Modulates Swine Gut Microbiota and Improves Growth Performance of Nursery Pigs When Combined with Peptide Cocktail
| Autor: | Feilong Deng, Jiangchao Zhao, Charles V Maxwell, Tsungcheng Tsai, Robert Story, Joshua Knapp, Xiaoyuan Wei, Kristopher Bottoms |
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| Rok vydání: | 2020 |
| Předmět: |
0301 basic medicine
Microbiology (medical) nursery pigs 030106 microbiology chemistry.chemical_element Weanling Peptide Zinc Biology Gut flora Body weight Microbiology Article 03 medical and health sciences Weaned piglets Virology peptide cocktail medicine Food science lcsh:QH301-705.5 chemistry.chemical_classification growth performance gut microbiota biology.organism_classification Diarrhea 030104 developmental biology lcsh:Biology (General) chemistry ZnO Rectal swab medicine.symptom |
| Zdroj: | Microorganisms Microorganisms, Vol 8, Iss 2, p 146 (2020) Volume 8 Issue 2 |
| ISSN: | 2076-2607 |
| DOI: | 10.3390/microorganisms8020146 |
| Popis: | Zinc has been very efficacious in reducing post-weaning diarrhea, whereas animal-derived peptides are suggested to improve the growth performance of weaned piglets. However, the combined effect of zinc and peptides on swine production and swine gut microbiota is still largely unknown. In this study, we followed 288 nursery pigs from the age of d30 to d60 to evaluate the growth performance and gut microbiota of weanling pigs subjected to different levels of a fish-porcine-microbial peptide cocktail (0.05%, 0.25%, and 0.5%) with or without the pharmaceutical level of zinc oxide (ZnO) (2500 ppm) supplementation in a nutrient-deficient diet. Rectal swab samples were collected from pigs with body weight (BW) approach average at each pen on d30, d42, and d60 to determine gut microbiota. Average daily gain (ADG) and BW in piglets fed high zinc (HZ) increased with increasing levels of peptide. The microbiota of the HZ group also diverged from those of the standard zinc (SZ) group from d30 to d60. Adding peptide did not alter community structure regardless of zinc supplementation. Collectively, these findings demonstrated that the pharmaceutical level of zinc as ZnO conditioned the gut community to the point where peptide could effectively restore growth performance in nursery pigs fed nutrient-deficient diets. |
| Databáze: | OpenAIRE |
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