Outbreak of Burkholderia cepacia complex infections associated with contaminated octenidine mouthwash solution, Germany, August to September 2018

Autor: Susanne K. Feldner, Manfred Haber, Alexander Mellmann, Fabian K. Berger, Barbara Gärtner, Hans-Joachim Schäfers, Sören L. Becker, Irem Karliova
Jazyk: angličtina
Rok vydání: 2022
Předmět:
Male
Epidemiology
Pyridines
Outbreak investigation
Mouthwashes
030501 epidemiology
Burkholderia cepacia
Microbiology
03 medical and health sciences
Nursing care
0302 clinical medicine
Postoperative Complications
Virology
Infection prevention
medicine
Infection control
Humans
In patient
030212 general & internal medicine
Aged
Aged
80 and over

Whole-genome sequencing
Cross Infection
Mouth
biology
Whole Genome Sequencing
business.industry
Burkholderia cepacia complex
Public Health
Environmental and Occupational Health

Healthcare-Associated Pneumonia
Outbreak
Thoracic Surgery
Hygiene
Burkholderia Infections
Contamination
medicine.disease
biology.organism_classification
Pneumonia
Anti-Infective Agents
Local

Imines
0305 other medical science
business
Drug Contamination
Bronchoalveolar Lavage Fluid
Rapid Communication
Zdroj: Eurosurveillance
DOI: 10.22028/d291-36537
Popis: Three German patients developed nosocomial pneumonia after cardiac surgery and had Burkholderia cepacia complex detected in respiratory specimens. Two patients died of septic multi-organ failure. Whole-genome sequencing detected genetically identical B. cepacia complex strains in patient samples, from a batch of octenidine mouthwash solution, which had been used for nursing care, as well as in samples obtained from the manufacturer during production. Contamination of medical products during manufacturing may lead to international outbreaks.
Databáze: OpenAIRE