Genome sequence of Aedes aegypti, a major arbovirus vector
| Autor: | Sergio Verjovski-Almeida, James E. Galagan, Ryan C. Kennedy, Zhiyong Xi, Jason R. Miller, Eric Eisenstadt, Kyanne R. Reidenbach, Robert V. Bruggner, Yu-Hui Rogers, Hadi Quesneville, Doreen Werner, Owen White, Alexander S. Raikhel, Mario Stanke, J. Spencer Johnston, Diane D. Lovin, Evgenia V. Kriventseva, Ian T. Paulsen, Kathryn S. Campbell, Norman H. Lee, Ewan Birney, Karyn Megy, Hean Koo, David Kulp, Shelby L. Bidwell, Jingsong Zhu, Philip Montgomery, Paolo Amedeo, Yongmei Zhao, Chinnappa D. Kodira, Javier Costas, Michael C. Schatz, Steven P. Sinkins, Claire M. Fraser-Liggett, Martin Shumway, Kurt LaButti, Akio Mori, Brendan J. Loftus, Manfred Grabherr, Eric O. Stinson, Frank H. Collins, Zhijian Jake Tu, Monique R. Coy, Matt Crawford, Janice P. Vanzee, William M. Gelbart, Joshua Orvis, Peter Arensburger, Chunhong Mao, Evgeny M. Zdobnov, Saul A. Kravitz, Suely Lopes Gomes, David DeCaprio, David G. Hogenkamp, Daniel Lawson, Dennis L. Knudson, David W. Severson, George Dimopoulos, Marcelo B. Soares, Sinéad B. O'Leary, Peter W. Atkinson, David M. Jaffe, Becky deBruyn, Martin Hammond, Ana L. T. O. Nascimento, Jim Biedler, Stefan Wyder, Jose M. C. Tubio, Bruce W. Birren, Catherine A. Hill, Chad Nusbaum, Eduardo Lee, Song Li, Susan E. Brown, Jennifer R. Wortman, James R. Hogan, Hamza El-Dorry, Qi Zhao, Linda Hannick, Carlos Frederico Martins Menck, Vishvanath Nene, Jonathan Crabtree, Steven L. Salzberg, Michael H. Holmes, Maria de Fatima Bonaldo, Quinghu Ren, Mihaela Pertea, Charles Roth, Evan Mauceli, Karin Eiglmeier, Horacio Naveira, Brian J. Haas, Qiandong Zeng, Neil F. Lobo, Jennifer R. Schneider |
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| Přispěvatelé: | The Institute for Genomic Research, The Institute for Genomic Research, Rockville, European Bioinformatics Institute [Hinxton] ( EMBL-EBI ), European Molecular Biology Laboratory [Hinxton], Broad Institute of MIT and Harvard ( BROAD INSTITUTE ), Broad Institute of MIT and Harvard, Virginia Polytechnic Institute and State University [Blacksburg], University College Dublin [Dublin] ( UCD ), Bloomberg School of Public Health, Johns Hopkins University ( JHU ) -Bloomberg School of Public Health, University of Geneva Medical School, Swiss Institute of Bioinformatics-University of Geneva Medical School, University of Notre Dame ( UND ), Harvard University [Cambridge], College of Agricultural Sciences Colorado State University, Colorado State University [Fort Collins] ( CSU ) -College of Agricultural Sciences, Northwestern University [Evanston], University of California [Riverside] ( UCR ), Department of Atmospheric, Oceanic and Planetary Physics [Oxford] ( AOPP ), University of Oxford [Oxford], Purdue University [West Lafayette], Centro Nacional de Genotipado Fundación Pública Galega de Medicina Xenómica Hospital Clínico Universitario de Santiago, Centro Nacional de Genotipado-Fundación Pública Galega de Medicina Xenómica-Hospital Clínico Universitario de Santiago, Institut Pasteur [Paris], Universidade de Sao Paulo Instituto de Quimica, Universidade de São Paulo ( USP ) -Instituto de Quimica, Texas A&M University [College Station], Joint Technology Center, University of Massachusetts [Amherst] ( UMass Amherst ), Universidade de Sao Paulo, Institute of Biomedical Sciences, Universidade de São Paulo ( USP ) -Institute of Biomedical Sciences, Instituto Butantan [São Paulo], Universidade da Coruña, University of Maryland [College Park], Institut Jacques Monod ( IJM ), Université Paris Diderot - Paris 7 ( UPD7 ) -Centre National de la Recherche Scientifique ( CNRS ), University of California [Santa Cruz] ( UCSC ), Complexo Hospitalario Universitario de Santiago, Universität Göttingen, Georg-August-Universität Göttingen, George Washington University Medical Center, George Washington University ( GW ), The Institute for Genomic Research (TIGR), European Bioinformatics Institute [Hinxton] (EMBL-EBI), EMBL Heidelberg, Broad Institute of MIT and Harvard (BROAD INSTITUTE), Harvard Medical School [Boston] (HMS)-Massachusetts Institute of Technology (MIT)-Massachusetts General Hospital [Boston], University College Dublin [Dublin] (UCD), Johns Hopkins Bloomberg School of Public Health [Baltimore], Johns Hopkins University (JHU), Swiss Institute of Bioinformatics [Lausanne] (SIB), Université de Lausanne (UNIL)-Université de Lausanne (UNIL)-University of Geneva Medical School, University of Notre Dame [Indiana] (UND), Colorado State University [Fort Collins] (CSU)-College of Agricultural Sciences, University of California [Riverside] (UCR), University of California, Department of Atmospheric, Oceanic and Planetary Physics [Oxford] (AOPP), Universidade de São Paulo (USP)-Instituto de Quimica, University of Massachusetts [Amherst] (UMass Amherst), University of Massachusetts System (UMASS), Universidade de São Paulo (USP)-Institute of Biomedical Sciences (ICB/USP), Universidade de São Paulo (USP), University of Maryland System, Institut Jacques Monod (IJM (UMR_7592)), Université Paris Diderot - Paris 7 (UPD7)-Centre National de la Recherche Scientifique (CNRS), University of California [Santa Cruz] (UCSC), Georg-August-University [Göttingen], The George Washington University (GW), George Washington University (GW), Université de Lausanne = University of Lausanne (UNIL)-Université de Lausanne = University of Lausanne (UNIL)-University of Geneva Medical School, Harvard University, University of California [Riverside] (UC Riverside), University of California (UC), University of Oxford, Institut Pasteur [Paris] (IP), Universidade de São Paulo = University of São Paulo (USP)-Instituto de Quimica, Universidade de São Paulo = University of São Paulo (USP)-Institute of Biomedical Sciences (ICB/USP), Universidade de São Paulo = University of São Paulo (USP), University of California [Santa Cruz] (UC Santa Cruz), Georg-August-University = Georg-August-Universität Göttingen, Zdobnov, Evgeny, Wyder, Stefan |
| Jazyk: | angličtina |
| Rok vydání: | 2016 |
| Předmět: |
0106 biological sciences
Male Transcription Genetic Genome Insect transposons receptors Genes Insect Aedes/ genetics/metabolism MESH: Genes Insect Yellow Fever/prevention & control/transmission MESH: Base Sequence 01 natural sciences Dengue/prevention & control/transmission MESH: Protein Structure Tertiary MESH: Arboviruses MESH : Insect Vectors MESH: Insect Proteins MESH : Anopheles gambiae MESH: Animals MESH : Arboviruses insects MESH: Yellow Fever superfamily ddc:616 0303 health sciences Anopheles MESH : Genes Insect 3. Good health yellow-fever mosquito anopheles-gambiae drosophila-melanogaster expression evolution organization Drosophila melanogaster MESH: DNA Transposable Elements [ SDV.BBM.GTP ] Life Sciences [q-bio]/Biochemistry Molecular Biology/Genomics [q-bio.GN] Multigene Family Public Health MESH : Protein Structure Tertiary MESH: Sex Characteristics Molecular Sequence Data MESH : Multigene Family MESH: Sex Determination (Genetics) MESH : Sex Determination (Genetics) Arbovirus Article 03 medical and health sciences Species Specificity [SDV.BBM.GTP]Life Sciences [q-bio]/Biochemistry Molecular Biology/Genomics [q-bio.GN] MESH: Anopheles gambiae Yellow Fever MESH: Species Specificity Humans MESH: Humans MESH: Molecular Sequence Data fungi MESH : Humans MESH : Sex Characteristics Membrane Transport Proteins Sex Determination Processes medicine.disease Insect Vectors Protein Structure Tertiary Sex Determination (Genetics) MESH: Multigene Family MESH: Female MESH : Sequence Analysis DNA MESH: Sequence Analysis DNA Drosophila melanogaster/genetics MESH : Molecular Sequence Data Odorant binding Insect Proteins/genetics Anopheles gambiae MESH: Dengue Genome MESH: Membrane Transport Proteins Dengue MESH : Membrane Transport Proteins Aedes Insect Vectors/ genetics/metabolism MESH : Drosophila melanogaster MESH : Female Membrane Transport Proteins/genetics Genetics MESH : Insect Proteins Sex Characteristics Multidisciplinary MESH: Synteny MESH: Aedes MESH : Genome Insect MESH : DNA Transposable Elements Insect Proteins Female Orthologous Gene MESH : Male MESH : Dengue Aedes aegypti MESH: Insect Vectors Biology 010603 evolutionary biology Synteny MESH: Drosophila melanogaster Protein Structure Tertiary/genetics MESH : Yellow Fever parasitic diseases medicine MESH : Species Specificity Animals 030304 developmental biology MESH : Aedes Base Sequence MESH: Genome Insect MESH: Transcription Genetic MESH : Synteny MESH : Transcription Genetic Sequence Analysis DNA biology.organism_classification MESH: Male DNA Transposable Elements MESH : Base Sequence MESH : Animals Arboviruses Anopheles gambiae/genetics/metabolism |
| Zdroj: | Science Science, American Association for the Advancement of Science, 2007, 316 (5832), pp.1718-23. 〈10.1126/science.1138878〉 Science, American Association for the Advancement of Science, 2007, 316 (5832), pp.1718-23. ⟨10.1126/science.1138878⟩ Science, 2007, 316 (5832), pp.1718-23. ⟨10.1126/science.1138878⟩ Science, Vol. 316, No 5832 (2007) pp. 1718-1723 |
| ISSN: | 0036-8075 1095-9203 |
| Popis: | We present a draft sequence of the genome of Aedes aegypti , the primary vector for yellow fever and dengue fever, which at ∼1376 million base pairs is about 5 times the size of the genome of the malaria vector Anopheles gambiae . Nearly 50% of the Ae. aegypti genome consists of transposable elements. These contribute to a factor of ∼4 to 6 increase in average gene length and in sizes of intergenic regions relative to An. gambiae and Drosophila melanogaster . Nonetheless, chromosomal synteny is generally maintained among all three insects, although conservation of orthologous gene order is higher (by a factor of ∼2) between the mosquito species than between either of them and the fruit fly. An increase in genes encoding odorant binding, cytochrome P450, and cuticle domains relative to An. gambiae suggests that members of these protein families underpin some of the biological differences between the two mosquito species. |
| Databáze: | OpenAIRE |
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