Partial protection of Sinopharm vaccine against SARS COV2 during recent outbreak in Bahrain

Autor: Mona Hmoud Al Sheikh, Mohamed Jahromi
Rok vydání: 2021
Předmět:
Zdroj: Microbial Pathogenesis
ISSN: 0882-4010
DOI: 10.1016/j.micpath.2021.105086
Popis: Background In order to impart immunity against SARS COV 2 in the community, the oil rich countries of the Gulf Cooperation Council (GCC) provided citizens and expatriates with free vaccination. Different types of vaccination brands were utilized for this purpose. The purpose of this study is to determine the efficacy of the different types of vaccinations used. Methods This is an observational analytical case study of one Bahraini family who were vaccinated with 1st, 2nd or no dose. Results Out of 22 double dose recipients of SARS COV2 vaccine, 20 were infected. Those 20 were vaccinated against SARS COV 2 using Sinopharm, the rest (2) were in direct contact with the source but were vaccinated against SARS COV 2 using other type of vaccine. Out of 26 single dose recipients of Sinopharm vaccine, 23 were infected. The other three were not in direct contact with the infected source. Social gathering has been the main source of transmission. The infection has been mild with headache, chest pain. From 20 cases with double dose vaccinations only one had a lung infection and needed hospitalization. Out of 23 cases with single dose vaccinations 10 were hospitalized due to lung infections. All family members who were not vaccinated were infected, three were hospitalized one of which was deceased due to diabetes mellitus complications. Conlcusion Sinopharm provides partial protection against SARS COV 2 infection. That might be due to lack of its potential to detect recent variations in the protein structure of spike(S) protein of virus.
Databáze: OpenAIRE
Externí odkaz: