Data supporting the angiotensin II activates MEL18 to deSUMOylate HSF2 for hypertension-related heart failure
| Autor: | Chih-Yang Huang, Chia-Hua Kuo, Pei-Ying Pai, Tsung-Jung Ho, Yueh-Min Lin, Ray-Jade Chen, Fuu-Jen Tsai, V. Vijaya Padma, Wei-Wen Kuo |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2017 |
| Předmět: |
0301 basic medicine
medicine.medical_specialty Lysine SUMO protein 030204 cardiovascular system & hematology lcsh:Computer applications to medicine. Medical informatics 03 medical and health sciences 0302 clinical medicine Downregulation and upregulation Internal medicine Medicine lcsh:Science (General) Multidisciplinary Angiotensin II receptor type 1 business.industry Human heart Medicine and Dentistry medicine.disease Angiotensin II 030104 developmental biology Endocrinology Heart failure Cardiac hypertrophy lcsh:R858-859.7 business lcsh:Q1-390 |
| Zdroj: | Data in Brief Data in Brief, Vol 16, Iss, Pp 521-526 (2018) |
| ISSN: | 2352-3409 |
| Popis: | In association with the published article “Inhibition of HSF2 SUMOylation via MEL18 upregulates IGF-IIR and leads to hypertension-induced cardiac hypertrophy” (Huang et al., 2017) [1] , this data article contains information about deSUMOylation of HSF2 on lysine 82 on angiotensin II (ANG II) -induced cardiac hypertrophy, which is mediated by MEL18. Isolated adult human whole heart tissue showed MEL18-mediated HSF2-IGF-IIR pathway is upregulated in hypertension human heart, compared to health human heart. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|