MRI of pituitary adenomas in acromegaly
Autor: | S. Gerber, Zouaoui A, Claude Marsault, Béatrice Marro, M. Sahel, K. Sag, Nader Sourour, N. Crozat |
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Rok vydání: | 1997 |
Předmět: |
Adenoma
Adult Gadolinium DTPA Male Pituitary gland Pathology medicine.medical_specialty Adolescent endocrine system diseases Contrast Media Paraneoplastic Endocrine Syndromes Pituitary adenoma Acromegaly Organometallic Compounds medicine Humans Pituitary Neoplasms Prolactinoma Radiology Nuclear Medicine and imaging Child Aged medicine.diagnostic_test Human Growth Hormone business.industry Magnetic resonance imaging Middle Aged Pentetic Acid medicine.disease Magnetic Resonance Imaging Prolactin medicine.anatomical_structure Pituitary Gland Coronal plane Female Neurology (clinical) Follicle Stimulating Hormone Cardiology and Cardiovascular Medicine business Hormone |
Zdroj: | Neuroradiology. 39:394-399 |
ISSN: | 1432-1920 0028-3940 |
Popis: | Adenomas causing acromegaly represent at least a quarter of pituitary adenomas. We studied 12 patients presenting with active acromegaly due to a pituitary adenoma with a 1.5 T superconductive MRI unit. All had T1-weighted sagittal and coronal sections before and after Gd-DTPA; six had coronal T2-weighted images. Surgical correlation was obtained in seven patients. Histologically, there were eight growth hormone (GH)-secreting and three mixed [GH and prolactin (PRL) secreting] adenomas, and one secreting GH, PRL and follicle-stimulating hormone. Macroadenomas (10) were more frequent than microadenomas (2). No correlation was found between serum GH and tumour size. There were nine adenomas in the lateral part of the pituitary gland; seven showed lateral or infrasellar invasion. Homogeneous, isointense signal on T1- and T2-weighted images was observed in six cases. Heterogeneous adenomas had cystic or necrotic components. |
Databáze: | OpenAIRE |
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