Practice Patterns for Eosinophilic Esophagitis Patients in Busan and Gyeongnam: A Korean Multicenter Database Study
| Autor: | Gwang Ha Kim, Hong Sub Lee, Kyoungwon Jung, Sang Young Seol, Moo In Park, Jae Hwang Cha, Su Jin Kim, Jin Lee, Sam Ryong Jee, Moon Won Lee, Jin Seok Jang |
|---|---|
| Rok vydání: | 2021 |
| Předmět: |
medicine.medical_specialty
Treatment response Proton pump inhibitors medicine.drug_class Proton-pump inhibitor Gastroenterology 03 medical and health sciences 0302 clinical medicine Internal medicine Medicine Eosinophilic esophagitis Practice patterns business.industry Medical record Database study medicine.disease 030220 oncology & carcinogenesis Cohort Original Article Steroids 030211 gastroenterology & hepatology Neurology (clinical) Proton pump inhibitor therapy business |
| Zdroj: | Journal of Neurogastroenterology and Motility |
| ISSN: | 2093-0887 2093-0879 |
| DOI: | 10.5056/jnm20069 |
| Popis: | Background/Aims The prevalence of eosinophilic esophagitis is increasing in Korea and there are few single-center studies regarding eosinophilic esophagitis in Korea. In particular, data about management for eosinophilic esophagitis are lacking. We aim to evaluate the practice patterns, including initial treatment and response, in the Busan city and Gyeongnam province area. Methods We retrospectively reviewed medical records to gain data on patient characteristics, medication, endoscopic images, and esophageal biopsy results. From January 2009 to December 2019, a total of 42 patients were diagnosed with eosinophilic esophagitis. Results The mean age was 50.7 (from 22 to 81) years and the cohort was predominantly male (78.6%, 33/42). The proton pump inhibitor was the preferred treatment as an initial trial for 64.3% (27/42) of patients, followed by swallowed topical steroids (16.7%, 7/42). Clinical improvement after proton pump inhibitor therapy was achieved in 88.9% (24/27) of patients. Two patients who did not achieve improvement showed a clinical and endoscopic response after swallowed topical steroids treatment. No patient received diet elimination or balloon dilatation therapy. Conclusions The treatment response of eosinophilic esophagitis was good in Busan city and Gyeongnam province area in Korea. Proton pump inhibitor therapy was the preferred and most effective treatment for eosinophilic esophagitis as the initial therapy. (J Neurogastroenterol Motil 2021;27:71-77) |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|