Description of clinical aspects and microscopy of the hair shaft of a carrier of familial monilethrix
| Autor: | Maria Angélica Tosi Ferreira, Rosana Cardoso Manique Rosa, Ana Elisa K. Bau, Paulo Ricardo Gazzola Zen, João Francisco de Oliveira Gonzales, Bruna Lixinski Diniz, Rafael Fabiano Machado Rosa, Maiara A. Floriani |
|---|---|
| Rok vydání: | 2018 |
| Předmět: |
Brittle hair
Hair characteristics integumentary system business.industry Clinical Biochemistry Hair shaft inheritance patterns hair Anatomy Genetic Condition medicine.disease hypotrichosis Pathology and Forensic Medicine monilethrix Medical Laboratory Technology Diffuse alopecia Monilethrix microscopy Pathology otorhinolaryngologic diseases medicine RB1-214 Hypotrichosis sense organs business |
| Zdroj: | Jornal Brasileiro de Patologia e Medicina Laboratorial, Vol 54, Iss 5, Pp 333-335 (2018) |
| ISSN: | 1676-2444 |
| DOI: | 10.5935/1676-2444.20180055 |
| Popis: | Monilethrix is a genetic condition that affects the hair shaft. We describe a family with this disease, focusing on its clinical aspects and microscopic hair characteristics. The patient was a 10-year-old female with history of hypotrichosis. In addition to diffuse alopecia, there was brittle hair, with ruptures in the hair shaft at different levels. The hair had a nodular appearance at naked eye. Other family members had the same symptoms, what indicates an autosomal dominant pattern of inheritance. Microscopic analysis revealed capillary fibers with areas of elliptical nodular appearance interspersed with regions of dystrophic constriction. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|