Effects of iron deficiency anemia on peripapillary and macular vessel density determined using optical coherence tomography angiography on children
| Autor: | Muhammet Furkan Korkmaz, Mehmet Erol Can, Elif Güler Kazancı |
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| Rok vydání: | 2020 |
| Předmět: |
Male
Fovea Centralis medicine.medical_specialty Adolescent Fundus Oculi Visual Acuity Optic disk Perimeter 03 medical and health sciences Cellular and Molecular Neuroscience chemistry.chemical_compound 0302 clinical medicine 030225 pediatrics Ophthalmology medicine Humans Prospective Studies Fluorescein Angiography Child Mean corpuscular volume Anemia Iron-Deficiency medicine.diagnostic_test biology business.industry Retinal Vessels Retinal medicine.disease Sensory Systems Capillaries Ferritin Cross-Sectional Studies chemistry Iron-deficiency anemia Child Preschool 030221 ophthalmology & optometry biology.protein Serum iron Female sense organs Hemoglobin business Tomography Optical Coherence Follow-Up Studies |
| Zdroj: | Graefe's Archive for Clinical and Experimental Ophthalmology. 258:2059-2068 |
| ISSN: | 1435-702X 0721-832X |
| DOI: | 10.1007/s00417-020-04633-8 |
| Popis: | To evaluate retinal vascular parameters by optical coherence tomography angiography (OCT-A) in iron deficiency anemia (IDA). Thirty-two patients with IDA (study group) and 30 healthy children (control group) were enrolled in the study. All subjects underwent a complete ocular examination. OCT-A scans were performed in a 6 × 6 mm area centered on the macula. Foveal avascular zone (FAZ), non-flow area (NFA), FAZ perimeter (PERIM), acircularity index (AI) of FAZ, and foveal density (FD) were measured in the superficial capillary plexus (SCP) and deep capillary plexus (DCP). SCP and DCP were also scanned centered on the optic disk. Hemoglobin (Hb), mean corpuscular volume (MCV), serum iron, total iron-binding capacity (TIBC), and ferritin were also studied and compared for both groups. The mean age was 12.22 ± 4.48 years (ranged 5–18 years) in the study group and 12.37 ± 3.76 years (ranged 6–18 years) in the control group. The mean FAZ value was 0.290 ± 0.09 mm2 in the study group and 0.298 ± 0.11 mm2 in the control group. The mean NFA value was 0.477 ± 0.10 mm2 in the study group and 0.486 ± 0.13 mm2 in the control group (p > 0.05). FD and AI were not statistically significant between the study group and control group (p > 0.05). The mean value for SCP was statistically significant between the study group and control group (p 0.05). The mean values for capillary density on optic disk were also statistically significant between the study group and control group (p |
| Databáze: | OpenAIRE |
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