Screening for Maternal Thyroid Dysfunction in Pregnancy: A Review of the Clinical Evidence and Current Guidelines
| Autor: | Elizabeth N. Pearce, Donny L.F. Chang |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2013 |
| Předmět: |
Pediatrics
medicine.medical_specialty Pregnancy Fetus endocrine system lcsh:RC648-665 endocrine system diseases business.industry Endocrinology Diabetes and Metabolism Thyroid disease Levothyroxine Review Article medicine.disease lcsh:Diseases of the endocrine glands. Clinical endocrinology Thyroid dysfunction Hypothyroxinemia medicine Observational study business medicine.drug Subclinical infection |
| Zdroj: | Journal of Thyroid Research, Vol 2013 (2013) Journal of Thyroid Research |
| ISSN: | 2042-0072 2090-8067 |
| Popis: | Observational studies have demonstrated that maternal thyroid dysfunction and thyroid autoimmunity in pregnancy may be associated with adverse obstetric and fetal outcomes. Treatment of overt maternal hyperthyroidism and overt hypothyroidism clearly improves outcomes. To date there is limited evidence that levothyroxine treatment of pregnant women with subclinical hypothyroidism, isolated hypothyroxinemia, or thyroid autoimmunity is beneficial. Therefore, there is ongoing debate regarding the need for universal screening for thyroid dysfunction during pregnancy. Current guidelines differ; some recommend an aggressive case-finding approach, whereas others advocate testing only symptomatic women or those with a personal history of thyroid disease or other associated medical conditions. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Plný text