Flow Changes in Orbital Vessels Detected with Color Doppler Ultrasound in Patients with Early Dysthyroid Optic Neuropathy
| Autor: | Igor Barišić, Goran Pelčić, Veljko Rogošić, Mladen Lešin, Lucija Vanjaka Rogošić |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2018 |
| Předmět: |
Central retinal artery
medicine.medical_specialty Graves' disease lcsh:Medicine 030209 endocrinology & metabolism Graves’ Ophthalmopathy Optic neuropathy Graves' ophthalmopathy 03 medical and health sciences 0302 clinical medicine Ultrasonography Doppler Color Graves’ Disease Optic Nerve Diseases Optic Nerve Injuries medicine.artery medicine Humans Ultrasonography Doppler Color Original Scientific Paper business.industry Gravesova oftalmopatija Gravesova bolest vidni živac bolesti ultrazvučno snimanje kolor dopler vidni živac ozljede lcsh:R Angiography General Medicine Blood flow medicine.disease Graves Disease Graves Ophthalmopathy Ophthalmic artery 030221 ophthalmology & optometry Optic nerve Radiology Internal carotid artery business |
| Zdroj: | Acta Clinica Croatica, Vol 57, Iss 2, Pp 301-306 (2018) Acta clinica Croatica Volume 57. Issue 2. Acta Clinica Croatica |
| ISSN: | 0353-9466 1333-9451 |
| Popis: | Thyroid-associated orbitopathy (TAO) is a common manifestation of Graves’ disease. Th e aim of the study was to assess the six percent of patients with TAO that develop dysthyroid optic neuropathy (DON), which is the most serious complication of TAO. As DON can cause permanent damage, it is essential to detect DON early when visual loss is still reversible. Color Doppler ultrasound is a noninvasive diagnostic method, which may be useful in early detection of DON. Th irty-six patients with confi rmed Graves’ disease and active TAO were included, 21 (58%) of them with early DON (eDON) and 15 (42%) free from any signs of eDON. All study patients underwent Doppler ultrasound examination to determine the blood fl ow rates in the internal carotid artery, ophthalmic artery, and central retinal artery. Study results showed color Doppler ultrasound examination to have a potential to detect orbital blood fl ow changes in patients with eDON. Early detection of DON may result in earlier treatment and prevention of permanent optic nerve damage. Problemi štitnjače i povezane orbitopatije (TAO) najčešća su manifestacija Gravesove bolesti. Cilj ove studije bio je objasniti 6% bolesnika s TAO kod kojih se razvila distiroidna optička neuropatija (DON), koja je ujedno najozbiljnija komplikacija TAO. S obzirom na to da DON može izazvati trajno oštećenje vida, vrlo ga je važno rano prepoznati dok je vidna funkcija još očuvana i reverzibilna. Obojeni Dopplerov ultrazvuk je neinvanzivna dijagnostička metoda koja je vrlo djelotvorna u ranom otkrivanju DON-a. U studiju je bilo uključeno 36 bolesnika s dijagnosticiranom Gravesovom bolesti i TAO-om, od kojih je 21 (58%) bolesnik imao rani DON (early DON, eDON), dok 15 (42%) bolesnika nije imalo znakova eDON-a. Svakom ispitaniku učinjen je obojeni Dopplerov ultrazvuk kako bi se odredio stupanj protoka krvi (cirkulacije) u unutarnjoj karotidnoj arteriji, oftalmičkoj arteriji i središnjoj retinalnoj arteriji. Rezultati su pokazali da pregled obojenim Dopplerovim ultrazvukom ima visok potencijal u ranoj dijagnostici promjena cirkulacije u orbiti kod bolesnika s ranim eDON-om. Rano otkrivanje DON-a može pomoći u ranijem liječenju i prevenciji trajnog oštećenja vidnoga živca. |
| Databáze: | OpenAIRE |
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