Survey of diagnostic and typing capacity for enterovirus infection in Italy and identification of two echovirus 30 outbreaks
| Autor: | Giada Gori, Gabriele Buttinelli, Patrizia Bagnarelli, Elisabetta Pagani, Lucia Collini, Daniela Cimini, Stefano Fontana, Katia Marinelli, Stefano Fiore, Valter Carraro, Elisa Masi, Concetta Amato, Paola Stefanelli, Vania Moroni |
|---|---|
| Rok vydání: | 2021 |
| Předmět: |
0301 basic medicine
medicine.medical_specialty Echovirus 030106 microbiology Disease medicine.disease_cause Disease Outbreaks 03 medical and health sciences 0302 clinical medicine Surveys and Questionnaires Virology Poliomyelitis eradication Enterovirus Infections Viral meningitis Humans Medicine 030212 general & internal medicine Retrospective Studies business.industry Public health virus diseases Outbreak medicine.disease Enterovirus B Human Poliomyelitis Infectious Diseases Italy Emergency medicine Enterovirus business |
| Zdroj: | Journal of Clinical Virology. 137:104763 |
| ISSN: | 1386-6532 |
| DOI: | 10.1016/j.jcv.2021.104763 |
| Popis: | Background Enterovirus infections can cause a variety of illnesses, ranging from asymptomatic infections to severe illness and death. Aim To support polio eradication activities, in February 2019, the WHO Regional Reference Laboratory for polio in Italy, at the National Institute of Public Health (Istituto Superiore di Sanita), promoted an investigation on non-polio enterovirus laboratory capacity, with the support of the Italian Ministry of Health. The aim was to collect data on the assays used routinely for diagnostic purposes and to characterize enterovirus outbreaks strains by sequence analysis of the Viral Protein 1 region. Methods A questionnaire was administered to public health laboratories through all Italian Regions for 2018 and subsequently, an electronic form for lab-confirmed enterovirus infection reported from February 2019 to January 2020, including patients clinical characteristics, and laboratory data was distributed through 25 laboratories participating the survey. Results Overall, a homogenous laboratory capacity for enterovirus infection diagnosis was found and 21,000 diagnostic tests were retrospectively reported in 2018. Then, in 2019, two outbreaks of Echovirus 30 were identified and confirmed by molecular analyses. Conclusion These results underline the need monitor the circulation of non-polio enterovirus to ascertain the real burden of the disease in the country. |
| Databáze: | OpenAIRE |
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