Field and Laboratory Alcohol Detection With 2 Types of Transdermal Devices
| Autor: | A Scott McKnight, Paul R. Marques |
|---|---|
| Rok vydání: | 2009 |
| Předmět: |
Adult
Male medicine.medical_specialty Alcohol Drinking Medicine (miscellaneous) Poison control Alcohol Breath tester Toxicology chemistry.chemical_compound Skin Physiological Phenomena Skin surface medicine Humans False Negative Reactions Monitoring Physiologic Transdermal Jurisprudence Ethanol business.industry Electrochemical Techniques Surgery Psychiatry and Mental health chemistry Anesthesia Fuel cells Female Detection rate business Alcohol consumption |
| Zdroj: | Alcoholism: Clinical and Experimental Research. 33:703-711 |
| ISSN: | 1530-0277 0145-6008 |
| DOI: | 10.1111/j.1530-0277.2008.00887.x |
| Popis: | Background: Two types of transdermal electrochemical sensors that detect alcohol at the skin surface were evaluated. One, the AMS SCRAM TM device, is locked onto the ankle and is based on a fuel cell sensor; the other, a Giner WrisTAS TM device, worn on the wrist, is based on a proton exchange membrane. SCRAM is used by several court systems in the United States to monitor alcohol offenders, WrisTAS, a research prototype, is not commercially available. Methods: The 2 devices were worn concurrently by 22 paid research subjects (15 men, 7 women), for a combined total of 96 weeks. Subjects participated in both laboratory-dosed drinking to a target of 0.08 g ⁄ dl blood alcohol concentration (BAC), and normal drinking on their own; all subjects were trained to use and carry a portable fuel-cell breath tester for BAC determinations. Overall 271 drinking episodes with BAC ‡ 0.02 g ⁄ dl formed the signal for detection—60 from laboratory dosing, and 211 from self-dosed drinking, with BAC ranging from 0.02 to 0.230 g ⁄ dl (mean 0.077 g ⁄ dl). Results: False negatives were defined as a transdermal alcohol concentration response equivalent |
| Databáze: | OpenAIRE |
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