Tagged MEG measures binocular rivalry in a cortical network that predicts alternation rate
| Autor: | Sylvain Baillet, Elizabeth Bock, Jeremy D. Fesi, Janine D. Mendola |
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| Rok vydání: | 2019 |
| Předmět: |
Male
genetic structures Vision Social Sciences Diagnostic Radiology 0302 clinical medicine Animal Cells Functional Magnetic Resonance Imaging Medicine and Health Sciences Psychology Visual Cortex Neurons Cerebral Cortex Temporal cortex Brain Mapping Vision Binocular Multidisciplinary medicine.diagnostic_test Radiology and Imaging 05 social sciences Magnetoencephalography Brain Magnetic Resonance Imaging medicine.anatomical_structure Medicine Sensory Perception Female Anatomy Cellular Types Research Article Adult Binocular rivalry Imaging Techniques Science Models Neurological Neuroimaging Research and Analysis Methods 050105 experimental psychology Ocular dominance 03 medical and health sciences Ocular System Diagnostic Medicine Vision Monocular medicine Humans 0501 psychology and cognitive sciences Monocular Optical illusion Cognitive Psychology Biology and Life Sciences Cell Biology eye diseases Visual cortex Cellular Neuroscience Eyes Cognitive Science Perception Nerve Net Head Neuroscience Binocular vision Photic Stimulation 030217 neurology & neurosurgery |
| Zdroj: | PLoS ONE PLoS ONE, Vol 14, Iss 7, p e0218529 (2019) |
| ISSN: | 1932-6203 |
| DOI: | 10.1371/journal.pone.0218529 |
| Popis: | Binocular rivalry (BR) is a dynamic visual illusion that provides insight into the cortical mechanisms of visual awareness, stimulus selection, and object identification. When dissimilar binocular images cannot be fused, perception switches every few seconds between the left and right eye images. The speed at which individuals switch between alternatives is a stable, partially heritable trait. In order to isolate the monocular and binocular processes that determine the speed of rivalry, we presented stimuli tagged with a different flicker frequency in each eye and applied stimulus-phase locked MEG source imaging. We hypothesized that the strength of the evoked fundamental or intermodulation frequencies would vary when comparing Fast and Slow Switchers. Ten subjects reported perceptual alternations, with mean dominance durations between 1.2-4.0 sec. During BR, event-related monocular input in V1, and broadly in higher-tier ventral temporal cortex, waxed and waned with the periods of left or right eye dominance/suppression. In addition, we show that Slow Switchers produce greater evoked intermodulation frequency responses in a cortical network composed of V1, lateral occipital, posterior STS, retrosplenial & superior parietal cortices. Importantly, these dominance durations were not predictable from the brain responses to either of the fundamental tagging frequencies in isolation, nor from any responses to a pattern rivalry control condition, or a non-rivalrous control. The novel cortical network isolated, which overlaps with the default-mode network, may contain neurons that compute the level of endogenous monocular difference, and monitor accumulation of this conflict over extended periods of time. These findings are the first to relate the speed of rivalry across observers to the 'efficient coding' theory of computing binocular differences that may apply to binocular vision generally. |
| Databáze: | OpenAIRE |
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