The Reduction Of Methylene Blue By Nervous Tissue

Autor: H. T. Ricketts
Rok vydání: 1904
Předmět:
Zdroj: Journal of Infectious Diseases. 1:590-598
ISSN: 1537-6613
0022-1899
DOI: 10.1093/infdis/1.4.590
Popis: A number of years ago Ehrlich pointed out the ability of living cells to decolorize (i. e., reduce) solutions of methylene blue. Later, Neisser and Wechsbergf devised an application of this phenomenon to determine the cytocidal effect of some cellular poisons upon leucocytes. They found that living leucocytes were able to reduce the dye quantitatively, but when they were killed by heat, alcohol, an immune leucotoxic serum, or staphylococcus "leucocidin," they lost this power. Other cells, when fresh (spermatozoa, pancreas, kidney), also reduced the dye, but not after treatment with an injurious agent (alcohol). Living microorganisms had a similar effect, which was lost on treating them with a bactericidal substance. Ferments and bacterial toxins had
Databáze: OpenAIRE