COVID-19 and Undiagnosed Pre-diabetes or Diabetes Mellitus Among International Migrant Workers in Singapore
| Autor: | Barbara Helen Rosario, Anindita Santosa, Shafi Humaira, Jeriel L Tan, Wann Jia Loh, Seow Yen Tan, Sharifah Munirah Alhamid, Troy H Puar, Theik Di Oo, Joan Khoo, Primavera Galinato, Louis Y Tee, Raymond Kok Choon Fong, Jaime Chien |
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| Jazyk: | angličtina |
| Rok vydání: | 2020 |
| Předmět: |
Adult
Male Pediatrics medicine.medical_specialty Population Risk Assessment Undiagnosed Diseases international migrant worker Prediabetic State 03 medical and health sciences Young Adult 0302 clinical medicine Diabetes mellitus medicine Humans 030212 general & internal medicine education pre-diabetes (pre-DM) Retrospective Studies Original Research Transients and Migrants education.field_of_study Singapore impaired glucose tolerance (IGT) business.industry SARS-CoV-2 030503 health policy & services Medical record lcsh:Public aspects of medicine Public Health Environmental and Occupational Health COVID-19 lcsh:RA1-1270 Odds ratio Middle Aged medicine.disease Confidence interval Hypokalemia Pneumonia diabetes mellitus Public Health medicine.symptom 0305 other medical science business Hyponatremia |
| Zdroj: | Frontiers in Public Health, Vol 8 (2020) Frontiers in Public Health |
| ISSN: | 2296-2565 |
| Popis: | Objective: Migrant workers, a marginalized and under-resourced population, are vulnerable to coronavirus disease 2019 (COVID-19) due to limited healthcare access. Moreover, metabolic diseases-such as diabetes mellitus (DM), hypertension, and hyperlipidemia-predispose to severe complications and mortality from COVID-19. We investigate the prevalence and consequences of undiagnosed metabolic illnesses, particularly DM and pre-diabetes, in international migrant workers with COVID-19. Methods: In this retrospective analysis, we analyzed the medical records of international migrant workers with laboratory-confirmed COVID-19 hospitalized at a tertiary hospital in Singapore from April 21 to June 1, 2020. We determined the prevalence of DM and pre-diabetes, and analyzed the risk of developing complications, such as pneumonia and electrolyte abnormalities, based on age and diagnosis of DM, and pre-diabetes. Results: Two hundred and fouty male migrant workers, with mean age of 44.2 years [standard deviation (SD), 8.5years], were included. Twenty one patients (8.8%) were diagnosed with pre-diabetes, and 19 (7.9%) with DM. DM was poorly controlled with a mean HbA1c of 9.9% (SD, 2.4%). 73.7% of the patients with DM and all the patients with pre-diabetes were previously undiagnosed. Pre-diabetes was associated with higher risk of pneumonia [odds ratio (OR), 10.8, 95% confidence interval (CI), 3.65-32.1; P < 0.0001], hyponatremia (OR, 8.83; 95% CI, 1.17-66.6; P = 0.0342), and hypokalemia (OR, 4.58; 95% CI, 1.52-13.82; P = 0.0069). Moreover, patients with DM or pre-diabetes developed COVID-19 infection with lower viral RNA levels. Conclusions: The high prevalence of undiagnosed pre-diabetes among international migrant workers increases their risk of pneumonia and electrolyte abnormalities from COVID-19. |
| Databáze: | OpenAIRE |
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