High grade cervical intraepithelial neoplasia positive biopsy: the importance of accurate pre-operative workup

Autor: Valeria Dubini, Flavia Sorbi, Dora Pavone, Irene Turrini, Felice Petraglia, Francesca Malentacchi, Cecilia Bussani, Massimiliano Fambrini, Giulia Fantappiè, Karin L. Andersson, Chiara Coco
Rok vydání: 2021
Předmět:
Zdroj: Minerva Ginecologica. 72
ISSN: 1827-1650
0026-4784
DOI: 10.23736/s0026-4784.20.04587-6
Popis: BACKGROUND In cervical cancer screening programs, women with abnormal cytology and confirmation by biopsy are referred for colposcopy for histological evaluation. METHODS We characterized the presence and the genotype of HPV by Linear Array HPV genotyping assay in cytological samples collected from about 400 women undergoing conization, with reported high CIN grade after biopsy. RESULTS The most prevalent genotype was HPV 16, with an increasing presence depending on the severity of the CIN and with the highest incidence in the 26-35 age range. In the group of younger women (
Databáze: OpenAIRE