Differential Recovery in Early- and Late-Onset Delayed Facial Palsy Following Vestibular Schwannoma Resection

Autor: Ryojo Akagami, Stephano Chang, Ivan Despot, Charles Dong, Serge Makarenko, Brian D. Westerberg
Rok vydání: 2019
Předmět:
Zdroj: Operative Neurosurgery. 18:34-40
ISSN: 2332-4260
2332-4252
DOI: 10.1093/ons/opz083
Popis: BACKGROUND Delayed facial palsy (DFP) after resection of vestibular schwannomas (VS) is worsening of facial nerve function after an initially normal postoperative result. OBJECTIVE To characterize different types of DFP, compare recovery rates, and review of series of outcomes in patients following resection of VS. METHODS Between 2001 and 2017, 434 patients (51% female) with VS underwent resection. We categorized the patients who developed facial palsy into groups based on timing of onset after surgery, immediate facial palsy (IFP), early-onset DFP (within 48 h), and late-onset DFP (after 48 h). Introduction of facial nerve motor-evoked potentials (fMEP) in 2002 and a change of practice utilizing perioperative minocycline in 2005 allowed for historical analysis of these interventions. RESULTS Mean age of study cohort was 49.1 yr (range 13-81 yr), with 19.8% developing facial palsy. The late-onset DFP group demonstrated a significantly faster recovery than the early-onset DFP group (2.8 ± 0.5 vs 47 ± 8 wk, P
Databáze: OpenAIRE