DOSE-DEPENDENCE OF SUPEROVULATION RESPONSE IN MICE TO TWO INJECTIONS OF PMSG

Autor: B. E. Eleftheriou, C. M. Christenson
Rok vydání: 1972
Předmět:
Zdroj: Reproduction. 29:287-289
ISSN: 1741-7899
1470-1626
DOI: 10.1530/jrf.0.0290287
Popis: Studies of the induction of superovulation by exogenous gonadotrophins have been made in various rodents (Rowlands & Parkes, 1966). Generally, it has been accepted that pregnant mare's serum gonadotrophin (pmsg) acts to stimulate follicular growth, preparing the follicles for ovulation, thus mimick¬ ing the endogenous follicle-stimulating hormone (fsh), while the subsequent human chorionic gonadotrophin (hcg) acts like the luteinizing hormone (lh), to stimulate the release of ova from the matured follicles. However, hcg injection is unnecessary for the release of ova from properly primed follicles (Zarrow & Quinn, 1963). The present study demonstrates that superovulation
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