The operative management of screen-detected breast cancers
| Autor: | M D, Crawford, A V, Biankin, M T, Rickard, M J, Coleman, R, West, F W, Niesche, S R, Renwick |
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| Rok vydání: | 2000 |
| Předmět: |
Oncology
Adult medicine.medical_specialty Multivariate analysis medicine.medical_treatment Biopsy Breast Neoplasms Breast cancer Internal medicine Cytology Medicine Mammography Humans Mass Screening Breast skin and connective tissue diseases Lymph node Mastectomy Aged Aged 80 and over Breast conservation medicine.diagnostic_test Screen detected business.industry Patient Selection General Medicine Middle Aged medicine.disease medicine.anatomical_structure Lymphatic Metastasis Surgery Female Radiotherapy Adjuvant New South Wales business |
| Zdroj: | The Australian and New Zealand journal of surgery. 70(3) |
| ISSN: | 0004-8682 |
| Popis: | Background: Mammographic screening for breast cancer not only reduces the overall mortality from breast cancer but allows greater opportunities for breast-conserving operations. The predicted degree of breast conservation is not being realized, but is increasing in centres that have published their results. Methods: The operative management of breast cancers diagnosed by BreastScreen Central and Eastern Sydney Screening and Assessment Service were compared between two time periods: January 1988–December 1992 (group 1) and January 1993–December 1995 (group 2). The rate of breast conservation, and other data were compared between the two periods. An attempt was made with multivariate analysis to identify some of the factors that made mastectomy rather than conservation more likely. Results: There were 723 cancers detected that were suitable for analysis (group 1, n = 273; group 2, n = 450). In group 1 the breast conservation rate was 42.9%; this increased significantly to 60.4% in group 2 (P < 0.001). The data were examined to determine if there was any other factor that had changed over the time periods which might account for the increased rate of breast conservation. The use of pre-operative diagnostic techniques such as fine needle aspirate cytology and core biopsy increased significantly. Multivariate analysis comparing the differences in patient age, diagnostic technique, tumour type, grade, size, location and lymph node status, both independently and compositely did not account for the increase in breast conservation in group 2. Conclusion: The increase in breast conservation is due to other factors such as the surgeons’ approach and patient attitude. The use of pre-operative, minimally invasive tissue sampling techniques is increasing. |
| Databáze: | OpenAIRE |
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