Giant Condylomata Acuminata of Buschke-Lowenstein Associated With Paraneoplastic Hypercalcemia
| Autor: | Arash Heidari, Piruthiviraj Natarajan, Mark Rivera, Fredrick Venter, Macsen Viehweg, Everardo Cobos |
|---|---|
| Rok vydání: | 2018 |
| Předmět: |
squamous cell carcinoma
medicine.medical_specialty Epidemiology Case Report Histopathological examination Genital warts 03 medical and health sciences 0302 clinical medicine paraneoplastic hypercalcemia lcsh:Pathology medicine Basal cell 030212 general & internal medicine Human papillomavirus human papillomavirus skin and connective tissue diseases Safety Risk Reliability and Quality Cancer Human papillomavirus types giant condylomata acuminata lcsh:R5-920 HPV vaccination business.industry Prevention Buschke Lowenstein tumor virus diseases Hpv vaccination medicine.disease Dermatology Buschke-Lowenstein Tumor 030220 oncology & carcinogenesis lcsh:Medicine (General) business Safety Research lcsh:RB1-214 genital warts E6 and E7 oncogenes |
| Zdroj: | Journal of Investigative Medicine High Impact Case Reports Journal of Investigative Medicine High Impact Case Reports, Vol 6 (2018) |
| ISSN: | 2324-7096 |
| DOI: | 10.1177/2324709618758348 |
| Popis: | Low-risk human papillomavirus types 6 and 11 can manifest as giant condylomata acuminata (GCA) of Buschke-Lowenstein. Up to 50% of GCA can slowly progress over years to fungating, invasive tumors. The malignant potential is attributed to unique immune evading abilities of the human papillomavirus. A 42-year-old male presented with pain and foul-smelling discharge from his genital warts. The histopathological examination of the mass showed invasive squamous cell carcinoma, and it was associated with paraneoplastic hypercalcemia. The timely removal of long-standing GCA in order to prevent a carcinomatous transition is a priority. |
| Databáze: | OpenAIRE |
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