UV decontamination of personal protective equipment with idle laboratory biosafety cabinets during the COVID-19 pandemic

Autor: Ju Li, Masahiro Hitomi, Nikhil Krishnan, Kyle J. Card, Dena Crozier, Andrew Dhawan, Gleb Kuzmin, Sean A. Diehl, Vishhvaan Gopalakrishnan, Jennifer L. Cadnum, Jacob G. Scott, Jeff Maltas, Gary An, Curtis J. Donskey, Davis T. Weaver, Julia Pelesko, Jessica A. Scarborough, Tanush Jagdish, Nathan Farrokhian, Benjamin D. McElvany, Emily Dolson, Enze Tian, Geoff Sedor, Emily Ho, Mina N. Dinh, Jinhan Mo, Eshan S. King
Jazyk: angličtina
Rok vydání: 2021
Předmět:
0301 basic medicine
Viral Diseases
business.product_category
Light
Pulmonology
Sanitization
Epidemiology
Respirators
Biosafety
Medical Conditions
0302 clinical medicine
Pandemic
Health care
Medicine and Health Sciences
Public and Occupational Health
Respirator
Decontamination
Multidisciplinary
Physics
Electromagnetic Radiation
Masks
Human decontamination
Containment of Biohazards
030210 environmental & occupational health
Infectious Diseases
Physical Sciences
Engineering and Technology
Medicine
Safety Equipment
Medical emergency
Safety
Research Article
Biotechnology
Infectious Disease Control
Coronavirus disease 2019 (COVID-19)
N95 Respirators
Ultraviolet Rays
Health Personnel
Science
030106 microbiology
Equipment
Bioengineering
Respiratory Disorders
03 medical and health sciences
Ultraviolet Radiation
Equipment Reuse
medicine
Humans
Radiometry
Pandemics
Personal protective equipment
SARS-CoV-2
business.industry
Biology and Life Sciences
COVID-19
Covid 19
Dose-Response Relationship
Radiation
medicine.disease
Health Care
Respiratory Infections
Medical Devices and Equipment
Preventive Medicine
Business
Ultraviolet C
Laboratories
Zdroj: PLoS ONE, Vol 16, Iss 7, p e0241734 (2021)
PLoS ONE
ISSN: 1932-6203
Popis: Personal protective equipment (PPE) is crucially important to the safety of both patients and medical personnel, particularly in the event of an infectious pandemic. As the incidence of Coronavirus Disease 2019 (COVID-19) increases exponentially in the United States and many parts of the world, healthcare provider demand for these necessities is currently outpacing supply. In the midst of the current pandemic, there has been a concerted effort to identify viable ways to conserve PPE, including decontamination after use. In this study, we outline a procedure by which PPE may be decontaminated using ultraviolet (UV) radiation in biosafety cabinets (BSCs), a common element of many academic, public health, and hospital laboratories. According to the literature, effective decontamination of N95 respirator masks or surgical masks requires UV-C doses of greater than 1 Jcm−2, which was achieved after 4.3 hours per side when placing the N95 at the bottom of the BSCs tested in this study. We then demonstrated complete inactivation of the human coronavirus NL63 on N95 mask material after 15 minutes of UV-C exposure at 61 cm (232 μWcm−2). Our results provide support to healthcare organizations looking for methods to extend their reserves of PPE.
Databáze: OpenAIRE
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