Fast selective trapping and release of picoliter droplets in a 3D microfluidic PDMS multi-trap system with bubbles
| Autor: | Ashutosh Yadav, Richard W. Rambach, Piotr Garstecki, Thomas Franke, Preetika Biswas |
|---|---|
| Rok vydání: | 2018 |
| Předmět: |
Polydimethylsiloxane
Chemistry Bubble 010401 analytical chemistry Microfluidics Surface acoustic wave technology industry and agriculture Pulse duration Nanotechnology 02 engineering and technology Trapping 021001 nanoscience & nanotechnology 01 natural sciences Biochemistry 0104 chemical sciences Analytical Chemistry Trap (computing) chemistry.chemical_compound Electrochemistry Environmental Chemistry Fluidics 0210 nano-technology Spectroscopy |
| Zdroj: | The Analyst. 143:843-849 |
| ISSN: | 1364-5528 0003-2654 |
| Popis: | The selective manipulation and incubation of individual picoliter drops in high-throughput droplet based microfluidic devices still remains challenging. We used a surface acoustic wave (SAW) to induce a bubble in a 3D designed multi-trap polydimethylsiloxane (PDMS) device to manipulate multiple droplets and demonstrate the selection, incubation and on-demand release of aqueous droplets from a continuous oil flow. By controlling the position of the acoustic actuation, individual droplets are addressed and selectively released from a droplet stream of 460 drops per s. A complete trapping and releasing cycle can be as short as 70 ms and has no upper limit for incubation time. We characterize the fluidic function of the hybrid device in terms of electric power, pulse duration and acoustic path. |
| Databáze: | OpenAIRE |
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